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Portrait de Prof. Jean Rodriguez
AMU iSm2 Service 531
Campus Scientifique de St Jérôme
Marseille cedex 20
0491 28 9187

1984 : PhD of Speciality at the University of Aix-Marseille
1984 : Recruted by the CNRS as Attaché de Recherche
1987 : PhD in Sciences at the University of Aix-Marseille
1988 : Postdoctoral reseach associate, University of California (Berkeley), supervisor: Prof K.P.C. Vollhardt
1989 : Promoted Chargé de Recherche de 1ère classe at CNRS
1992 : Habilitation at the University of Aix-Marseille
1998 : Promoted Directeur de Recherche at the CNRS
2002 : Nominated full Professor at the University of Aix-Marseille


1998 : Prize from ACROS-French Chemical Society in organic chemistry
2009 : Prize from the Société Chimique de France, Division Chimie Organique
2013 : Member of the Editorial Board of European Journal of Organic Chemistry
2013 : Distinguished Senior Member of the Société Chimique de France
2021 : Grand Prix de l'Académie des Sciences Emile Jungfleisch


Bachelor Degree in Chemistry
*Ionic and Polar Rearrangements in Organic Synthesis

Master Degree in Chemistry
*Strategies in Synthetic Organic Chemistry (Retrosynthetic analysis, Total synthesis, Protection and Deprotection of functional groups)
*New Selective Multiple Bond-Forming Transformations (Metallo- and Organocatalyzed Consecutive, Domino and Multicomponent reactions)
*Recent Applications of enantioselective metallo- and organocatalysis in Organic Synthesis

Collaborations et groupes

Dr Muriel AMATORE, Assitant Professor
Dr Damien BONNE, Assistant Professor
Dr Xavier BUGAUT, Full professor
Dr Thierry CONSTANTIEUX, Full Professor
Dr Yoann COQUEREL, Associate Researcher from the CNRS
Dr Adrien QUINTARD, Associate Researcher from the CNRS
Dr. Manuel BARDAY, Postdoctoral Research Associate (2022)
Dr. Expédite Yen-PON, Postdoctoral Research Associate (2022)
Pierre BOUILLAC, PhD student (2019-2022)
Birane DIOP, PhD student (2022)
Arthur GAUCHERAND, PhD student (2020-2023)
Na SHAO, PhD student (2020-2024)

Responsabilités administratives

1999-2007 : Member of Bureau National de la S F C, Division Chimie Organique
2000-2006 : Expert auprès du ministère dans le cadre de la MSTP4
2004-2007 : Director of the Reseach Unit SYMBIO
2006-2011 : Chargé de Mission à l'Institut de chimie du CNRS (section 12)
2008- Present : Director of the Institut des Sciences Moléculaires de Marseille (iSm2)       

Publications (210)
Reference Résumé graphique HAL

Synthesis of Pyrrolo[2,3- c ]isoquinolines via the Cycloaddition of Benzyne with Arylideneaminopyrroles: Photophysical and Crystallographic Study

Juan-Carlos Castillo, Alexis Tigreros, Yoann Coquerel, Jean Rodriguez, Mario Macías, Jaime Portilla, ACS Omega, 2019, 4, 17326-17339. <hal-02354816>

Enantioselective organocatalytic activation of vinylidene–quinone methides (VQMs)

Jean Rodriguez, Damien Bonne, Chemical Communications, 2019, 55, 11168-11170. <hal-02354840>

Acyl Transfer Strategies as Transient Activations for Enantioselective Synthesis

Jean Rodriguez, Adrien Quintard, SYNTHESIS, 2019, 51, 1923-1934. <hal-02279701>

Experimental and theoretical studies of (4 + 1) annulations between α‐oxoketenes and stable phosphorous, nitrogen, or sulfur ylides

David Pierrot, Michel Rajzmann, Yannick Carissan, Jean Rodriguez, Damien Bonne, Yoann Coquerel, Journal of Physical Organic Chemistry, 2019, e3939. <hal-02059903>

Design and synthesis of simplified speciophylline analogues and β-carbolines as active molecules against Plasmodium falciparum

David Pierrot, Veronique Sinou, Sok-Siya Bun, Daniel Parzy, Nicolas Taudon, Jean Rodriguez, Evelyne Ollivier, Damien Bonne, Drug Development Research, 2019, 80, 133-137. <hal-02083576>

Enantioselective Ir-Catalyzed Bidirectional Reductive Coupling

Adrien Quintard, Jean Rodriguez, Organic Letters, 2019, 21, 453-456. <hal-01987319>

An Organocatalytic Two-atom Ring Expansion Approach to Optically Active Glutarimides

Yun-Long Wei, Yajun Ren, Damien Mailhol, Michel Rajzmann, Jean Rodriguez, Yoann Coquerel, Advanced Synthesis and Catalysis, 2019, 361, 2992-3001. <hal-02331641>

Spirobicyclic and Tetracyclic Pyrazolidinones: Syntheses and Properties

Fabien Perez, Thibault Leveille, Mathilde Bertolotti, Jean Rodriguez, Yoann Coquerel, European Journal of Organic Chemistry, 2019, 2019, 6034-6043. <hal-02331699>

Enantioselective Organocatalytic Four-Atom Ring Expansion of Cyclobutanones: Synthesis of Benzazocinones

Yirong Zhou, Yun-Long Wei, Jean Rodriguez, Yoann Coquerel, Angewandte Chemie International Edition, 2019, 58, 456-460. <hal-02331607>

Organo- and Copper-Multi-Catalyzed Pseudo Four-Component Access to gem -Difluorohydrins

Angela Ricucci, Jean Rodriguez, Adrien Quintard, European Journal of Organic Chemistry, 2018, 2018, 3697 - 3700. <hal-01850449>


Ouvrages (3)
Reference Résumé graphique HAL

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

Eds.: J. Rodriguez, D. Bonne, John Wiley & Sons, Inc., Hoboken, NJ, USA, 2015.

Jean Rodriguez, Damien Bonne. Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis. John Wiley & Sons, 2015, 978-1-118-67271-6. ⟨hal-01323433⟩


David Pierrot, Damien Bonne, Jean Rodriguez 2014, e-EROS Encyclopedia of Reagents for Organic Synthesis. 1–5.

Chapitres d'ouvrages (9)
Reference Résumé graphique HAL

Yoann Coquerel, Jean Rodriguez. The Wolff Rearrangement: Tactics, Strategies and Recent Applications in Organic Synthesis. Molecular Rearrangements in Organic Synthesis, Johne Wiley & Sons, pp.59-84, 2015, 978-1-118-34796-6. ⟨hal-01224316⟩

1,3-Dicarbonyls in Multicomponent Reactions

X. Bugaut, T. Constantieux, Y. Coquerel, J. Rodriguez, In Multicomponent Reactions in Organic Synthesis, Eds.: J. Zhu, Q. Wang, M.-X. Wang, Wiley-VCH, Weinheim, 2014, Chap. 5, pp 109-158.

Xavier Bugaut, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez. 1,3-Dicarbonyls in Multicomponent Reactions. J. Zhu, Q. Wang, M.-X. Wang. Multicomponent Reactions in Organic Synthesis, Wiley-VCH, Weinheim, pp.109-158, 2014, 978-3-527-33237-3. ⟨hal-01133604⟩

Reactions Involving an alpha,beta-Unsaturated Compound as Electrophilic Component with the Michael Addition as the Key Step

J. Rodriguez, D. Bonne, Y. Coquerel, T. Constantieux, dans 'Multicomponent Reactions 2', 'Science of Synthesis Reference Library', T. J. J. Müller, Ed., Thieme, Stuttgart, 2013, Chap. 2.1.1, p. 1-36.

Stereoselective Multicomponent Reactions: from Simple 1,3-Dicarbonyls to Functionalized Chiral Heterocycles

D. Bonne, Y. Coquerel, T. Constantieux, J. Rodriguez in Targets in Heterocyclic Systems - Chemistry and Properties, Vol. 15, Eds.: O. A. Attanasi, D. Spinelli, Societa? Chimica Italiana, Roma, 2011, pp. 140-163. 

Utilisation des dérivés 1,3-dicarbonylés dans les réactions domino et multicomposé

Damien Bonne, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez Techniques de l'Ingénieur 2010, CHV2210

Damien Bonne, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez. Utilisation des dérivés 1,3-dicarbonylés dans les réactions domino et multicomposé. Ideas in Chemistry and Molecular Sciences: Advances in Synthetic Chemistry, pp.CHV2210, 2010. ⟨hal-00680619⟩

Yoann Coquerel, Thomas Boddaert, Marc Presset, Damien Mailhol, Jean Rodriguez. Multiple Bond-Forming Transformations: the Key Concept towards Eco-compatible Synthetic Organic Chemistry. Ideas in Chemistry and Molecular Sciences, Vol.1 Advances in synthetic chemistry, Wiley-VCH, Weinheim, pp.187-202, 2010, 3527325395. ⟨hal-00681017⟩

Maria del Mar Sanchez Duque, Christophe Allais, Nicolas Isambert, Thierry Constantieux, Jean Rodriguez. beta-diketo building blocks for MCRs-based syntheses of heterocycles. Topics in Heterocyclic Chemistry, Springer, pp.227-277, 2010, ⟨10.1007/7081_2010_26⟩. ⟨hal-00680508⟩

Brevets (1)
Reference Résumé graphique HAL

Adrien Quintard, Céline Sperandio, Jean Rodriguez. NOVEL FLUORINATED POLYOLS AND THEIR USE AS ORGANOGELATORS. France, Patent n° : WO/2019/238582. 2019. ⟨hal-02878986⟩