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Portrait de Prof. Jean Rodriguez
AMU iSm2 Service 531
Campus Scientifique de St Jérôme
Marseille cedex 20
0491 28 9187

1984 : PhD of Speciality at the University of Aix-Marseille
1984 : Recruted by the CNRS as Attaché de Recherche
1987 : PhD in Sciences at the University of Aix-Marseille
1988 : Postdoctoral reseach associate, University of California (Berkeley), supervisor: Prof K.P.C. Vollhardt
1989 : Promoted Chargé de Recherche de 1ère classe at CNRS
1992 : Habilitation at the University of Aix-Marseille
1998 : Promoted Directeur de Recherche at the CNRS
2002 : Nominated full Professor at the University of Aix-Marseille


1998 : Prize from ACROS-French Chemical Society in organic chemistry 2009 : Prize from the Société Chimique de France, Division Chimie Organique 2013 : Member of the Editorial Board of European Journal of Organic Chemistry 2013 : Distinguished Senior Member of the Société Chimique de France 2013 : Dr Paul Janssen invited lecturer, Beerse (Belgium)


Bachelor Degree in Chemistry
*Ionic and Polar Rearrangements in Organic Synthesis

Master Degree in Chemistry
*Strategies in Synthetic Organic Chemistry (Retrosynthetic analysis, Total synthesis, Protection and Deprotection of functional groups)
*New Selective Multiple Bond-Forming Transformations (Metallo- and Organocatalyzed Consecutive, Domino and Multicomponent reactions)
*Recent Applications of enantioselective metallo- and organocatalysis in Organic Synthesis

Collaborations et groupes

Dr Damien BONNE, Assistant Professor
Dr Xavier BUGAUT, Assistant Professor
Dr Thierry CONSTANTIEUX, Full Professor
Dr Yoann COQUEREL, Associate Researcher from the CNRS
Dr Adrien QUINTARD, Associate Researcher from the CNRS
Dr Rodolphe BEAU, Postdoctoral Reseach Associate (2016-2018)
Dr Nicolas DALMASSO, Postdoctoral Associate (2016-2018)
Yasmin REVIVOT, PhD student (2017-2020)
Peng LIU, PhD student (2017-2020)
Brian CASTRO, PhD student (2017-2020)
Céline SPERANDIO, PhD student (2016-2019)
Yun-Long WEI PhD student (2015-2018)

Responsabilités administratives

1999-2007 : Member of Bureau National de la S F C, Division Chimie Organique
2000-2006 : Expert auprès du ministère dans le cadre de la MSTP4
2004-2007 : Director of the Reseach Unit SYMBIO
2006-2011 : Chargé de Mission à l'Institut de chimie du CNRS (section 12)
2008- Present : Director of the Institut des Sciences Moléculaires de Marseille (iSm2)       

Publications (210)
Reference Résumé graphique HAL

Design, Synthesis and Biological evaluation of a bivalent μ opiate and adenosine A1 receptors antagonist

Smitha C. Mathew, Nandita Ghosh, Youlet By, Aurélie Berthault, Marie-Alice Virolleaud, Louis Carrega, Gaëlle Chouraqui, Laurent Commeiras, Jocelyne Condo, Mireille Attolini, Anouk Gaudel-Siri, Jean Ruf, Jean-Luc Parrain, Jean Rodriguez, Régis Guieu, Bioorganic and Medicinal Chemistry Letters, 2009, 19, 6736-6739. <hal-00679622>

Consecutive reactions with sulfoximines: a direct access to 2-sulfonimidoylylidene tetrahydrofurans and 6-sulfonimidoylmethyl- 3,4-dihydro-2H-pyrans

Marie-Alice Virolleaud, Vellaisamy Sridharan, Damien Mailhol, Damien Bonne, Cyril Bressy, Gaëlle Chouraqui, Laurent Commeiras, Yoann Coquerel, Jean Rodriguez, Tetrahedron, 2009, 65, 9756-9764. <hal-00676864>

Organocatalytic Activity of N-Heterocyclic Carbenes in the Michael Addition of 1,3-Dicarbonyls: Application to a Stereoselective Spirocyclization Sequence

Thomas Boddaert, Yoann Coquerel, Jean Rodriguez, Advanced Synthesis and Catalysis, 2009, 351, 1744-1748. <hal-00678242>

Synthesis and palladium-catalysed isomerisation of fused polycyclic tetrahydrofurans : efficient and stereoselective one-pot domino construction of functionalised bridged bicyclo[n.2.1] ring systems

Pierre-Yves Roger, Fabien Blondeau, David Bensa, Thierry Constantieux, Jean Rodriguez, Molecular Diversity, 2009, 13, 469-473. <hal-00681054>

Microwave-Assisted Wolff Rearrangement of Cyclic 2-Diazo-1,3-Diketones: An Eco-compatible Route to alpha-Carbonylated Cycloalkanones

Marc Presset, Yoann Coquerel, Jean Rodriguez, Journal of Organic Chemistry, 2009, 74, 415-418. <hal-00677647>

Microwave-assisted Cross-metathesis of Acrylonitrile

Thomas Boddaert, Yoann Coquerel, Jean Rodriguez, Comptes Rendus. Chimie, 2009, 12, 872-875. <hal-00678249>

Highly efficient synthesis of trans-β,γ-unsaturated-α-keto amides

Christophe Allais, Thierry Constantieux, Jean Rodriguez, SYNTHESIS, 2009, 13, 469-473. <hal-00681064>

Bicyclic 5-6 Systems with One Bridgehead (Ring Junction) Nitrogen Atom: Two Extra Heteroatoms 0:2

J. Rodriguez, T. Constantieux. Comprehensive Heterocyclic Chemistry III, AR Katritzky, CA Ramsden, EFV Scriven and RJK Taylor, Eds., Elsevier: Oxford, 2008, Vol. 11, pp 629 - 644.

Sequential Organocatalyzed Michael Addition/[3 + 2]-Heterocyclization for the Stereoselective Synthesis of Fused-Isoxazoline Precursors of Enantiopure Cyclopentanoids

Damien Bonne, Lydie Salat, Jean-Pierre Dulcère, Jean Rodriguez, Organic Letters, 2008, 10, 5409-5412. <hal-00677496>

Synthetic Studies Towards Guaianolide Sesquiterpene Lactones

Isabelle Reboul, Thomas Boddaert, Yoann Coquerel, Jean Rodriguez, European Journal of Organic Chemistry, 2008, 5379-5382. <hal-00678253>


Ouvrages (3)
Reference Résumé graphique HAL

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

Eds.: J. Rodriguez, D. Bonne, John Wiley & Sons, Inc., Hoboken, NJ, USA, 2015.

Jean Rodriguez, Damien Bonne. Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis. John Wiley & Sons, 2015, 978-1-118-67271-6. ⟨hal-01323433⟩


David Pierrot, Damien Bonne, Jean Rodriguez 2014, e-EROS Encyclopedia of Reagents for Organic Synthesis. 1–5.

Chapitres d'ouvrages (9)
Reference Résumé graphique HAL

Yoann Coquerel, Jean Rodriguez. The Wolff Rearrangement: Tactics, Strategies and Recent Applications in Organic Synthesis. Molecular Rearrangements in Organic Synthesis, Johne Wiley & Sons, pp.59-84, 2015, 978-1-118-34796-6. ⟨hal-01224316⟩

1,3-Dicarbonyls in Multicomponent Reactions

X. Bugaut, T. Constantieux, Y. Coquerel, J. Rodriguez, In Multicomponent Reactions in Organic Synthesis, Eds.: J. Zhu, Q. Wang, M.-X. Wang, Wiley-VCH, Weinheim, 2014, Chap. 5, pp 109-158.

Xavier Bugaut, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez. 1,3-Dicarbonyls in Multicomponent Reactions. J. Zhu, Q. Wang, M.-X. Wang. Multicomponent Reactions in Organic Synthesis, Wiley-VCH, Weinheim, pp.109-158, 2014, 978-3-527-33237-3. ⟨hal-01133604⟩

Reactions Involving an alpha,beta-Unsaturated Compound as Electrophilic Component with the Michael Addition as the Key Step

J. Rodriguez, D. Bonne, Y. Coquerel, T. Constantieux, dans 'Multicomponent Reactions 2', 'Science of Synthesis Reference Library', T. J. J. Müller, Ed., Thieme, Stuttgart, 2013, Chap. 2.1.1, p. 1-36.

Stereoselective Multicomponent Reactions: from Simple 1,3-Dicarbonyls to Functionalized Chiral Heterocycles

D. Bonne, Y. Coquerel, T. Constantieux, J. Rodriguez in Targets in Heterocyclic Systems - Chemistry and Properties, Vol. 15, Eds.: O. A. Attanasi, D. Spinelli, Societa? Chimica Italiana, Roma, 2011, pp. 140-163. 

Utilisation des dérivés 1,3-dicarbonylés dans les réactions domino et multicomposé

Damien Bonne, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez Techniques de l'Ingénieur 2010, CHV2210

Damien Bonne, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez. Utilisation des dérivés 1,3-dicarbonylés dans les réactions domino et multicomposé. Ideas in Chemistry and Molecular Sciences: Advances in Synthetic Chemistry, pp.CHV2210, 2010. ⟨hal-00680619⟩

Yoann Coquerel, Thomas Boddaert, Marc Presset, Damien Mailhol, Jean Rodriguez. Multiple Bond-Forming Transformations: the Key Concept towards Eco-compatible Synthetic Organic Chemistry. Ideas in Chemistry and Molecular Sciences, Vol.1 Advances in synthetic chemistry, Wiley-VCH, Weinheim, pp.187-202, 2010, 3527325395. ⟨hal-00681017⟩

Maria del Mar Sanchez Duque, Christophe Allais, Nicolas Isambert, Thierry Constantieux, Jean Rodriguez. beta-diketo building blocks for MCRs-based syntheses of heterocycles. Topics in Heterocyclic Chemistry, Springer, pp.227-277, 2010, ⟨10.1007/7081_2010_26⟩. ⟨hal-00680508⟩

Brevets (1)
Reference Résumé graphique HAL

Adrien Quintard, Céline Sperandio, Jean Rodriguez. NOVEL FLUORINATED POLYOLS AND THEIR USE AS ORGANOGELATORS. France, Patent n° : WO/2019/238582. 2019. ⟨hal-02878986⟩