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Portrait de Dr. Cédric Colomban
AMU iSm2 AMU ECM iSm2 Service 452
Campus Scientifique de St Jérôme
Marseille cedex 20

Bioinspired Confined Catalysis

Caged bioinorganic complexes for efficient and selective catalytic transformations in confined spaces.

Robust metal-based catalysts for efficient transformations in complex mixtures

We get inspiration from the enzyme hydrophobic pockets, to reach an efficient protection of Cu(I) catalysts. We are interrested in caged ligands that protect the Cu-center from it deactivation by the reduced gluthathione GSH, without suffering from product inhibition effect, opening the way to efficient CuAAC transformations in complex media. (Chem. Commun. 2021, 57, 2281)

 Selective C-H oxidation via caged bioinspired catalysts.

       - Bioinspired catalysis

Aiming at reproducing the remarkable chemistry found in monooxygenases enzymes, the BCC group develop bioinspired catalysts displaying a cage structure (hydrophobic cavity) that act as a filter to select the targeted substrate. In partiular we have recently demonstrated that caged catalysts results in a more selective oxidation of methane compared to the corresponding models devoid of cavity. Current research aims at developing both efficent and selective C-H oxidation methods based on caged iron and copper complexes.

       -Straightforward preparation of enantiopure caged complexes.

We develop an inovative strategy to prepare bioinspired complexes with controlled helicity. Our methodology is based on enantiopure cage-ligands displaying a chiral cap. Chirality transfer phenomenom between the northern cap and the ligand control helicity at the southern metal core. (Chem. Commun. 2019, 55, 14158).

Publications (22)
Reference Résumé graphique HAL

Comparison of μ-nitrido diiron phthalocyanine – H 2 O 2 and Fenton systems in transformation of poly- and perfluorinated aromatics does not support the involvement of hydroxyl radicals

Cédric Colomban, Alexander Sorokin, Journal of Coordination Chemistry, 2018, 1 - 8. <hal-01855939>

Self-Assembled Cofacial Zinc-Porphyrin Supramolecular Nanocapsules as Tuneable 1 O 2 Photosensitizers

Cédric Colomban, Carles Fuertes-Espinosa, Sébastien Goeb, Marc Sallé, Miquel Costas, Lluis Blancafort, Xavi Ribas, Chemistry - A European Journal, 2018, 24, 4371 - 4381. <hal-01855930>

Design of Zn-, Cu-, and Fe-Coordination Complexes Confined in a Self-Assembled Nanocage

Cédric Colomban, Vlad Martin-Diaconescu, Teodor Parella, Sébastien Goeb, Cristina García-Simón, Julio Lloret-Fillol, Miquel Costas, Xavi Ribas, Inorganic Chemistry, 2018, 57, 3529 - 3539. <hal-01855934>

Copper(II) complexes of N 3 O ligands as models for galactose oxidase: Effect of variation of steric bulk of coordinated phenoxyl moiety on the radical stability and spectroscopy

Cédric Colomban, Christian Philouze, Florian Molton, Nicolas Leconte, Fabrice Thomas, Inorganica Chimica Acta Reviews, 2017, 481, 129-142. <hal-01639561>

Heteroleptic μ-nitrido diiron complex supported by phthalocyanine and octapropylporphyrazine ligands: Formation of oxo species and their reactivity with fluorinated compounds

Cédric Colomban, Evgenij Kudrik, Alexander Sorokin, Journal of Porphyrins and Phthalocyanines, 2017, 21, 345 - 353. <hal-01855999>

Reversible C 60 Ejection from a Metallocage through the Redox-Dependent Binding of a Competitive Guest

Cédric Colomban, György Szalóki, Magali Allain, Laura Gomez, Sébastien Goeb, Marc Sallé, Miquel Costas, Xavi Ribas, Chemistry - A European Journal, 2017, 23, 3016 - 3022. <hal-01855935>

Synthesis and characterization of μ-nitrido, μ-carbido and μ-oxo dimers of iron octapropylporphyrazine

Cédric Colomban, Alexander Sorokin, Evgenij Kudrik, Pavel Afanasiev, F. Albrieux, S. E. Nefedov, Dalton Transactions, 2015, 44, 2240 - 2251. <hal-01856001>

X-ray Absorption and Emission Spectroscopies of X-Bridged Diiron Phthalocyanine Complexes (FePc) 2 X (X = C, N, O) Combined with DFT Study of (FePc) 2 X and Their High-Valent Diiron Oxo Complexes

Cédric Colomban, Evgenij Kudrik, Valérie Briois, Janine Shwarbrick, Alexander Sorokin, Pavel Afanasiev, Inorganic Chemistry, 2014, 53, 11517-11530. <hal-02921803>

Iron Phthalocyanine

Cédric Colomban, SYNLETT, 2014, 25, 2521 - 2522. <hal-01856005>

Degradation of chlorinated phenols in water in the presence of H2O2 and water-soluble μ-nitrido diiron phthalocyanine

Cédric Colomban, Alexander Sorokin, Evgenij Kudrik, Pavel Afanasiev, Catalysis Today, 2014, 235, 14 - 19. <hal-01855998>