Dr. Marius REGLIER
Dr.
Marius
REGLIER
AMU iSm2 Service 342
Campus Scientifique de St Jérôme
13397
Marseille cedex 20
Téléphone :
Fax :
0491 28 84 40
Courriel :
ORCID ID: 0000-0002-8360-3098
Entrée :
01/01/2008
Parcours :
Education:
1975: Master in Sciences, Paul Cézanne Univ. Aix-Marseille III
1976: Chemical Ingeneer, Ecole Supérieure de Chimie de Marseille
1980: First Ph. D., Paul Cézanne Univ. Aix-Marseille III, September 26, 1980, Reactivity of non-conjugated dienes towards the catalytic system PdCl2/CuCl2: cyclisation and allylic oxidations (Pr. B. Waegell and Dr. A. Heumann)
1984: Second Ph. D. (thèse d’Etat), Pierre and Marie Curie Univ. Paris VI, December 18, 1984, Syntheses and Reactivity of Thia and 1-Aza-3-Cyclohexenes (Dr. S. Julia)
Experience:
1980-1984: CNRS Researcher (Attaché de Recherche), Ecole Normale Supérieure, Pierre and Marie Curie Univ. Paris VI, Dr. S. Julia
1985-1986: Research Fellow; University of Geneva, Switzerland, Pr. W. Oppolzer.
1986-1994: CNRS Researcher (CR1), Paul Cézanne Univ. Aix-Marseille III, Pr. B. Waegell
1989-1990: Research Fellow, Lab. of Cellular and Molecular Neurobiology, Gif/Yvette, Dr. J. Mallet.
1992: Visiting scientist, Johns Hopkins Univ., Baltimore, USA, Pr. K. D. Karlin.
1994-2018 : Senior scientist at CNRS (Directeur de Recherche), Aix-Marseille Université
2018-: CNRS Research Director emeritus (DREM)
Past administrative positions:
1996-2004: Member of the organising committee of REncontres de Chimie Organique Biologique (President for RECOB8, 2000)
2000-2004: Appointed member of the CNRS Comité National section 20
2001-2006: Founding President of the GIS CNRS/Univ. Paul Cézanne Club CNRS Métalloprotéines et Modèles
2006-2011: Member of the scientific committee of the Indo-French Center for the Promotion of the Advanced Research (CEFIPRA/IFCPAR)
2006-2008: Founding Director of the FRE CNRS 3005 BiosCiences
2007-2009: Member of the scientific committee of the ANR program blanc
2009-2012: Vice-president of the ANR program Retour Post-doctorant
2009-2017: Head of the team BiosCiences
(iSm2 UMR CNRS 7313)
2010-2015: French member of the Management Committee Action COST CM1003, Biological Oxidation Reactions, Mechanisms and Design of new Catalysts
2012-2018: Scientific officier at the Institut de Chimie du CNRS
Distinctions :
2002: Docteur et de Madame Henri Labbé prize from the French Academy of Science.
2002: JSPS fellowship
2004: France Berkeley Fund with J. P. Klinman, Department of Chemistry UC Berkeley
2011: CNRS Excellence in Science
2014: Chaire d’excellence from FAPESP (São Paulo Research Fondation) in University of São Paulo (USP).
Enseignements :
Aix Marseille Université
- Synthetic biology, M2 degree course in Master Chemistry
Université de Paris
- Redox bio-inorganic chemistry, M2 degree course in Master Frontiers in Chemistry
Università degli Studi di catania (Italy), october 2021
- Introduction of non-canonical amino acids in protein synthesis in Doctoral course degree
Ecole de l’INSERM Liliane Bettencourt, double degree course Medecine/Science
- Chemical aspects of Epigenetic, L2 course for medical students
- Chemistry of the S-Adenosyl Methionine cofactor (MOOC)
The S-Adenosyl Methionine cofactor
resolution.mpg
Thématiques :
Activation of small molecules (O2, H2, H2O, CO2 …) by metalloenzymes and their biomimetic/bioinspired models.
A) Cu-containing monooxygenases (in collaboration with J. A. Simaan, M. Orio, B. Faure, R. Hardré and C. Decroos)
Focused on Tyrosinase (Ty), Dopamine beta-Hydroxylase (DbH), Peptidylglycine alpha-Amidating Monooxygenase (PAM), particulate Methane MonoOxygenase (pMMO) and Lytic Polysaccharide MonoOxygenase (LPMO):
- Functional and structural metalloenzyme models
- Mechanism-based inhibitors of DbH, PAM and Ty
- Purification and genetic expression of copper-containing monooxygenases.
Selected publications on Tyrosinase inhibition: Inorg. Chem. 2009, 48, 10874–10876 ; Eur. J. Chem. Med. 2011, 46, 4330-4335 ; Chem. Eur. J. 2011, 17, 13482–13494 ; ChemBioChem 2012, 13, 559-565 ; Chem. Eur. J. 2013, 19, 3655-3664 ; Chem. Commun. 2014, 50, 308-3010 ; ChemBioChem 2014,15(9), 1325–1333 ; Inorg. Chem. 2014, 53, 12848-12858 ; J. Agr. Food Chem. 2016, 64, 2925-2931 ; Current Topics in Medicinal Chemistry 2016, 16(27), 3033-3047 ; ACS Med. Chem. Lett. 2017, 8 (1), 55-60 ; ChemEur J. 2021, 27, 4384-4393..
Selected publications on LPMO: Inorg. Chem. 2017, 56, 1023-1026 ; FEBS J. 2020, 287, 3298–33143.
Selected publications on copper bioinorganic chemistry: Inorg. Chem. 2013, 52(10), 5824-5830 ; Eur. J. Inorg. Chem. 2015, 3512–3518 ; Inorg. Chem. 2016, 55, 8263-8266 ; Dalton trans. 2016, 45, 15994-16000 ; ChemPlusChem 2017, 82, 615-624 ; Inorg. Chem. 2017, 56, 7704-7719 ; Inorg. Chim. Acta 2018,481, 113-119 ; Chem. Eur. J. 2018, 24, 5213-5224 ; Dalton trans. 2018, 47, 9665-9676 ; Inorg. Chem. 2018, 57, 12364−12375 ; Eur. J. Inorg. Chem. 2018, 5039–5046 and “Series in Chemistry, Energy and Environment”, Eds.K. Kadish and R. Guilard, World Scientific. Vol. 5: “Bioinspired Chemistry: From Enzymes to Synthetic Models.”, Ed. M. Réglier, 2019, pp. 185-263 ; Eur. J. Inorg. Chem. 2020, 4549-4555 ; Angew. Chem. Int. Ed. Engl. 2019, 58, 14605 –14609 and ChemBioChem 2021, 22, 443-459.
B) [NiFe]hydrogenase (in collaboration with M. Orio, B. Faure and R. Hardré)
Biomimetic chemistry focused on functional models to perform the reversible transformation of protons to H2.
Publications: ChemCatChem 2017, 9, 2262-2268, Eur. J. Inorg. Chem. 2018, 2259-2266 ; Chem. Eur. J. 2018, 24, 8779-8786 ; Dalton Trans. 2020, 49, 5064–5073 ; ChemComm 2020, 56(75), 11106-11109.
C) Molybdenum-containing enzymes (in collaboration with O. Iranzo, M. Orio and R. Hardré)
Biomimetic chemistry focused on functional models of Formate dehydrogenases (Fdh) that perform the reversible transformation of CO2 into formate.
Publication: Eur. J. Inorg. Chem. 2018, 1427-1434 and J. Org. Chem. 2021, 86, 2210-2223.
D) Books and Chapters
- Copper Mononuclear Monooxygenases. M. Réglier and C. Belle in “Encyclopedia of Metalloproteins”, eds. R. H. Kretsinger, V. N. Uversky and E. A. Permyakov, Springer, 2013, pp. 723-729.
- 1-Aminocyclopropane-1-Carboxylic Acid Oxidase. A. J. Simaan and M. Réglier in "2-Oxoglutarate-Dependent Oxygenases", eds. C. Schofield and R. P. Hausinger. Royal Society of Chemistry, 2015, RSC Metallobiology Series No. 3, pp. 423-437.
- “Bioinspired Chemistry: From Enzymes to Synthetic Models.”, Ed. M. Réglier, In “Series in Chemistry, Energy and Environment”, Eds. K. Kadish and R. Guilard, World Scientific. Vol. 5: 2019.
Collaborations et groupes :
French Collaborations
Drs. Yves Le Mest and Nicolas Le Poul, CEMCA UMR CNRS 6521, Université de Bretagne Occidentale
Drs. Aurore Thibon Pourret, Hélène Jamet and Catherine Belle, DCM UMR CNRS 5250, Université Grenoble Alpes
Dr. Vincent Artero, LCBM UMR CNRS/CEA 5249, Université Grenoble Alpes
Pr. Bruno Guigliareli, BIP UMR CNRS 7281, Aix Marseille Université
Dr. Jean Guy Berrin, BBF UMR INRA, Aix Marseille Université
International Collaborations
Pr. Franc Meyer, Institut für Anorganische Chemie, Georg-August-Universität Göttingen (Germany)
Pr. Luigi Bubacco, Department of Biology, University of Padova (Italy)
Pr. Surajit Sinha, Department of Organic Chemistry, Indian Association for the Cultivation of Science, Kolkata (India)
Responsabilités administratives :
2016-: Scientific Committee Member of the CEEBIOS (Centre Européen d'Excellence en Biomimetisme de Senlis)
2017-: Scientific Committee Member of the COSMETHICS, Cosmethics at the confluence of beauty and health (CDP 2017, Cross Disciplinary Program of Université Grenoble Alpes)
Actions de vulgarisation :
Déclics: Member of the Association "Déclics" that promotes scientific research and its outlets among young people.
- 2019 Lycées Simone Veil and Saint Exupéry (Marseille)
- 2020 Lycée Simone Veil (Marseille)
- 2021 Lycées Périer, Simone Veil and Thiers (Marseille)
Apprentis Chercheurs: Member of the association "Les Apprentis Chercheurs" that allows high school students to develop a research project in a research laboratory.
- 2016/17 Skin whitening, a dangerous case of the tyrosinase inhibition
- 2017/18 Bacteria and antibacterials
- 2018/19 Fruit browning, ethylene and polyphenol oxidases
- 2019/20 Copper complexes and cancers
- 2020/21 Copper complexes and environment
Les Savanturiers: Mentoring in the association "Les Savanturiers" that mobilizes and federates schools (primary and high schools) and the scientific communities (Universities, CNRS …) to promote sciences in an educational program.
- 2018/19 Around earthworms in the ecosystems, with the primary school Rabelais in Creil (Oise).
- 2020/21 The world of microorganisms, with the primary school CM1/CM2 in Volonne (Alpes de Haute Provence
- 2021/22 The world of plants, with the primary school CM1/CM2 in Volonne (Alpes de Haute Provence
Publications (88)
Reference
Résumé graphique
HAL
New insights in the mechanism of the dioxygen activation catalyzed by the Dopamine beta-monoxygenase.
P. Slama, M. Reglier(2007) C. R. Chimie 10, 731-741.
✖
New Functional Model Complexes of Intradiol-Cleaving Catechol Dioxygenases: Properties and Reactivity of Cu(II)(L)(O2Ncat).
J. Kaizer, Z. Zsigmond, I. Ganszky, G. Speier, M. Giorgi, M. Reglier(2007) Inorg. Chem. 46, 4660-4666.
✖
Cerium(IV)-mediated oxidation of flavonol with relevance to flavonol 2,4-dioxygenase. Direct evidence for spin delocalization in the flavonoxy radical
József Kaizer, Ildikó Ganszky, Gábor Speier, Antal Rockenbauer, László Korecz, Michel Giorgi, M. Réglier, Serge Antonczak, Journal of Inorganic Biochemistry, 2007, 101, 893-899. <hal-01948933>
✖
Synthesis, structure and catalase mimics of novel homoleptic manganese(II) complexes of 1,3-bis(2′-pyridylimino)isoindoline, Mn(4R-ind)2 (R=H, Me)
József Kaizer, Gábor Baráth, Gábor Speier, M. Réglier, Michel Giorgi, Inorganic Chemistry Communications, 2007, 10, 292-294. <hal-01948935>
✖
Manganese and iron flavonolates as flavonol 2,4-dioxygenase mimics
József Kaizer, Gábor Baráth, József Pap, Gábor Speier, Michel Giorgi, M. Réglier, Chemical Communications, 2007, 5235. <hal-01948930>
✖
Characterization of Cu(II)-ACC Complexes and Conversion of the Bound ACC into Ethylene in the Presence of Hydrogen Peroxide. Detection of a Brown Intermediate at Low Temperature
Wadih Ghattas, Michel Giorgi, Christian Gaudin, Antal Rockenbauer, Marius Réglier, A. Jalila Simaan, Bioinorganic Chemistry and Applications, 2007, 2007, 43424. <hal-02299044>
✓
(O-Benzoylsalicylato)copper(II) complexes as synthetic enzyme-product models for flavonol 2,4-dioxygenase.
Kaizer, S. Góger, G. Speier, M. Reglier, M. Giorgi Inorg. Chem. Comm. 2006, 9, 251-254.
✖
{Chloro-[N-benzyl-bis-(2-pyridyl-methyl)amino]-copper(II)} perchlorate,[Cu(bnbpa)Cl]ClO4.
J. Kaizer, S. Góger, G. Speier, M. Giorgi, M. Reglier. Z. Kristallogr. NCS, 2006, 221, 75-76.
✖
Preparation and X-ray Structure of a Catecholato Copper(II) Complex with a Schönberg Adduct.
B. Tapodi, G. Speier, M. Giorgi, M. Reglier, T. Funabiki, L. Korecz, A. Rockenbauer. Inorg. Chem. Comm. 2006, 9, 367-370.
✖
Synthesis, structure and catalase-like activity of Cu(N-baa)2(phen) (phen = 1,10-phenanthroline, N-baaH = N-benzoylanthranilic acid).
J. Kaizer, T. Csay, G. Speier, M. Reglier and M. Giorgi. Inorg. Chem. Comm. 2006, 9, 1037-1039.
✖
Pages
Chapitres d'ouvrages (2)
Reference
Résumé graphique
HAL
A. Jalila Simaan, Alda Lisa Concia, Alessia Munzone, Maria-Chrysanthi Kafentzi, Amélie Kochem, et al.. Modeling the Mononuclear Copper Monooxygenase Active Site. Series on Chemistry, Energy and the Environment: Volume 5 Bioinspired Chemistry; From Enzymes to Synthetic Models, pp.185-263, 2019, ⟨10.1142/9789813274440_0008⟩. ⟨hal-02094996⟩
✖
A. Jalila Simaan, Marius Réglier. CHAPTER 20. 1-Aminocyclopropane-1-Carboxylic Acid Oxidase. 2-oxoglutarate-dependent oxygenases RSC Metallobiology Series, 3., pp.425-437, 2015, ⟨10.1039/9781782621959-00425⟩. ⟨hal-02095042⟩
✖
Dr.
Marius
REGLIER
Dr.
Marius
REGLIER
AMU iSm2 Service 342
Campus Scientifique de St Jérôme
13397
Marseille cedex 20
Téléphone :
Fax :
0491 28 84 40
Courriel :
ORCID ID: 0000-0002-8360-3098
Entrée :
01/01/2008
Parcours :
Education:
1975: Master in Sciences, Paul Cézanne Univ. Aix-Marseille III
1976: Chemical Ingeneer, Ecole Supérieure de Chimie de Marseille
1980: First Ph. D., Paul Cézanne Univ. Aix-Marseille III, September 26, 1980, Reactivity of non-conjugated dienes towards the catalytic system PdCl2/CuCl2: cyclisation and allylic oxidations (Pr. B. Waegell and Dr. A. Heumann)
1984: Second Ph. D. (thèse d’Etat), Pierre and Marie Curie Univ. Paris VI, December 18, 1984, Syntheses and Reactivity of Thia and 1-Aza-3-Cyclohexenes (Dr. S. Julia)
Experience:
1980-1984: CNRS Researcher (Attaché de Recherche), Ecole Normale Supérieure, Pierre and Marie Curie Univ. Paris VI, Dr. S. Julia
1985-1986: Research Fellow; University of Geneva, Switzerland, Pr. W. Oppolzer.
1986-1994: CNRS Researcher (CR1), Paul Cézanne Univ. Aix-Marseille III, Pr. B. Waegell
1989-1990: Research Fellow, Lab. of Cellular and Molecular Neurobiology, Gif/Yvette, Dr. J. Mallet.
1992: Visiting scientist, Johns Hopkins Univ., Baltimore, USA, Pr. K. D. Karlin.
1994-2018 : Senior scientist at CNRS (Directeur de Recherche), Aix-Marseille Université
2018-: CNRS Research Director emeritus (DREM)
Past administrative positions:
1996-2004: Member of the organising committee of REncontres de Chimie Organique Biologique (President for RECOB8, 2000)
2000-2004: Appointed member of the CNRS Comité National section 20
2001-2006: Founding President of the GIS CNRS/Univ. Paul Cézanne Club CNRS Métalloprotéines et Modèles
2006-2011: Member of the scientific committee of the Indo-French Center for the Promotion of the Advanced Research (CEFIPRA/IFCPAR)
2006-2008: Founding Director of the FRE CNRS 3005 BiosCiences
2007-2009: Member of the scientific committee of the ANR program blanc
2009-2012: Vice-president of the ANR program Retour Post-doctorant
2009-2017: Head of the team BiosCiences
(iSm2 UMR CNRS 7313)
2010-2015: French member of the Management Committee Action COST CM1003, Biological Oxidation Reactions, Mechanisms and Design of new Catalysts
2012-2018: Scientific officier at the Institut de Chimie du CNRS
Distinctions :
2002: Docteur et de Madame Henri Labbé prize from the French Academy of Science.
2002: JSPS fellowship
2004: France Berkeley Fund with J. P. Klinman, Department of Chemistry UC Berkeley
2011: CNRS Excellence in Science
2014: Chaire d’excellence from FAPESP (São Paulo Research Fondation) in University of São Paulo (USP).
Enseignements :
Aix Marseille Université
- Synthetic biology, M2 degree course in Master Chemistry
Université de Paris
- Redox bio-inorganic chemistry, M2 degree course in Master Frontiers in Chemistry
Università degli Studi di catania (Italy), october 2021
- Introduction of non-canonical amino acids in protein synthesis in Doctoral course degree
Ecole de l’INSERM Liliane Bettencourt, double degree course Medecine/Science
- Chemical aspects of Epigenetic, L2 course for medical students
- Chemistry of the S-Adenosyl Methionine cofactor (MOOC)
The S-Adenosyl Methionine cofactor
resolution.mpg
Thématiques :
Activation of small molecules (O2, H2, H2O, CO2 …) by metalloenzymes and their biomimetic/bioinspired models.
A) Cu-containing monooxygenases (in collaboration with J. A. Simaan, M. Orio, B. Faure, R. Hardré and C. Decroos)
Focused on Tyrosinase (Ty), Dopamine beta-Hydroxylase (DbH), Peptidylglycine alpha-Amidating Monooxygenase (PAM), particulate Methane MonoOxygenase (pMMO) and Lytic Polysaccharide MonoOxygenase (LPMO):
- Functional and structural metalloenzyme models
- Mechanism-based inhibitors of DbH, PAM and Ty
- Purification and genetic expression of copper-containing monooxygenases.
Selected publications on Tyrosinase inhibition: Inorg. Chem. 2009, 48, 10874–10876 ; Eur. J. Chem. Med. 2011, 46, 4330-4335 ; Chem. Eur. J. 2011, 17, 13482–13494 ; ChemBioChem 2012, 13, 559-565 ; Chem. Eur. J. 2013, 19, 3655-3664 ; Chem. Commun. 2014, 50, 308-3010 ; ChemBioChem 2014,15(9), 1325–1333 ; Inorg. Chem. 2014, 53, 12848-12858 ; J. Agr. Food Chem. 2016, 64, 2925-2931 ; Current Topics in Medicinal Chemistry 2016, 16(27), 3033-3047 ; ACS Med. Chem. Lett. 2017, 8 (1), 55-60 ; ChemEur J. 2021, 27, 4384-4393..
Selected publications on LPMO: Inorg. Chem. 2017, 56, 1023-1026 ; FEBS J. 2020, 287, 3298–33143.
Selected publications on copper bioinorganic chemistry: Inorg. Chem. 2013, 52(10), 5824-5830 ; Eur. J. Inorg. Chem. 2015, 3512–3518 ; Inorg. Chem. 2016, 55, 8263-8266 ; Dalton trans. 2016, 45, 15994-16000 ; ChemPlusChem 2017, 82, 615-624 ; Inorg. Chem. 2017, 56, 7704-7719 ; Inorg. Chim. Acta 2018,481, 113-119 ; Chem. Eur. J. 2018, 24, 5213-5224 ; Dalton trans. 2018, 47, 9665-9676 ; Inorg. Chem. 2018, 57, 12364−12375 ; Eur. J. Inorg. Chem. 2018, 5039–5046 and “Series in Chemistry, Energy and Environment”, Eds.K. Kadish and R. Guilard, World Scientific. Vol. 5: “Bioinspired Chemistry: From Enzymes to Synthetic Models.”, Ed. M. Réglier, 2019, pp. 185-263 ; Eur. J. Inorg. Chem. 2020, 4549-4555 ; Angew. Chem. Int. Ed. Engl. 2019, 58, 14605 –14609 and ChemBioChem 2021, 22, 443-459.
B) [NiFe]hydrogenase (in collaboration with M. Orio, B. Faure and R. Hardré)
Biomimetic chemistry focused on functional models to perform the reversible transformation of protons to H2.
Publications: ChemCatChem 2017, 9, 2262-2268, Eur. J. Inorg. Chem. 2018, 2259-2266 ; Chem. Eur. J. 2018, 24, 8779-8786 ; Dalton Trans. 2020, 49, 5064–5073 ; ChemComm 2020, 56(75), 11106-11109.
C) Molybdenum-containing enzymes (in collaboration with O. Iranzo, M. Orio and R. Hardré)
Biomimetic chemistry focused on functional models of Formate dehydrogenases (Fdh) that perform the reversible transformation of CO2 into formate.
Publication: Eur. J. Inorg. Chem. 2018, 1427-1434 and J. Org. Chem. 2021, 86, 2210-2223.
D) Books and Chapters
- Copper Mononuclear Monooxygenases. M. Réglier and C. Belle in “Encyclopedia of Metalloproteins”, eds. R. H. Kretsinger, V. N. Uversky and E. A. Permyakov, Springer, 2013, pp. 723-729.
- 1-Aminocyclopropane-1-Carboxylic Acid Oxidase. A. J. Simaan and M. Réglier in "2-Oxoglutarate-Dependent Oxygenases", eds. C. Schofield and R. P. Hausinger. Royal Society of Chemistry, 2015, RSC Metallobiology Series No. 3, pp. 423-437.
- “Bioinspired Chemistry: From Enzymes to Synthetic Models.”, Ed. M. Réglier, In “Series in Chemistry, Energy and Environment”, Eds. K. Kadish and R. Guilard, World Scientific. Vol. 5: 2019.
Collaborations et groupes :
French Collaborations
Drs. Yves Le Mest and Nicolas Le Poul, CEMCA UMR CNRS 6521, Université de Bretagne Occidentale
Drs. Aurore Thibon Pourret, Hélène Jamet and Catherine Belle, DCM UMR CNRS 5250, Université Grenoble Alpes
Dr. Vincent Artero, LCBM UMR CNRS/CEA 5249, Université Grenoble Alpes
Pr. Bruno Guigliareli, BIP UMR CNRS 7281, Aix Marseille Université
Dr. Jean Guy Berrin, BBF UMR INRA, Aix Marseille Université
International Collaborations
Pr. Franc Meyer, Institut für Anorganische Chemie, Georg-August-Universität Göttingen (Germany)
Pr. Luigi Bubacco, Department of Biology, University of Padova (Italy)
Pr. Surajit Sinha, Department of Organic Chemistry, Indian Association for the Cultivation of Science, Kolkata (India)
Responsabilités administratives :
2016-: Scientific Committee Member of the CEEBIOS (Centre Européen d'Excellence en Biomimetisme de Senlis)
2017-: Scientific Committee Member of the COSMETHICS, Cosmethics at the confluence of beauty and health (CDP 2017, Cross Disciplinary Program of Université Grenoble Alpes)
Actions de vulgarisation :
Déclics: Member of the Association "Déclics" that promotes scientific research and its outlets among young people.
- 2019 Lycées Simone Veil and Saint Exupéry (Marseille)
- 2020 Lycée Simone Veil (Marseille)
- 2021 Lycées Périer, Simone Veil and Thiers (Marseille)
Apprentis Chercheurs: Member of the association "Les Apprentis Chercheurs" that allows high school students to develop a research project in a research laboratory.
- 2016/17 Skin whitening, a dangerous case of the tyrosinase inhibition
- 2017/18 Bacteria and antibacterials
- 2018/19 Fruit browning, ethylene and polyphenol oxidases
- 2019/20 Copper complexes and cancers
- 2020/21 Copper complexes and environment
Les Savanturiers: Mentoring in the association "Les Savanturiers" that mobilizes and federates schools (primary and high schools) and the scientific communities (Universities, CNRS …) to promote sciences in an educational program.
- 2018/19 Around earthworms in the ecosystems, with the primary school Rabelais in Creil (Oise).
- 2020/21 The world of microorganisms, with the primary school CM1/CM2 in Volonne (Alpes de Haute Provence
- 2021/22 The world of plants, with the primary school CM1/CM2 in Volonne (Alpes de Haute Provence
Publications (88)
| Reference | Résumé graphique | HAL |
|---|---|---|
|
New insights in the mechanism of the dioxygen activation catalyzed by the Dopamine beta-monoxygenase. |
|
✖ |
|
New Functional Model Complexes of Intradiol-Cleaving Catechol Dioxygenases: Properties and Reactivity of Cu(II)(L)(O2Ncat). |
|
✖ |
|
Cerium(IV)-mediated oxidation of flavonol with relevance to flavonol 2,4-dioxygenase. Direct evidence for spin delocalization in the flavonoxy radical |
|
✖ |
|
Synthesis, structure and catalase mimics of novel homoleptic manganese(II) complexes of 1,3-bis(2′-pyridylimino)isoindoline, Mn(4R-ind)2 (R=H, Me) |
|
✖ |
|
Manganese and iron flavonolates as flavonol 2,4-dioxygenase mimics |
|
✖ |
|
Characterization of Cu(II)-ACC Complexes and Conversion of the Bound ACC into Ethylene in the Presence of Hydrogen Peroxide. Detection of a Brown Intermediate at Low Temperature |
|
✓ |
|
(O-Benzoylsalicylato)copper(II) complexes as synthetic enzyme-product models for flavonol 2,4-dioxygenase. |
|
✖ |
|
{Chloro-[N-benzyl-bis-(2-pyridyl-methyl)amino]-copper(II)} perchlorate,[Cu(bnbpa)Cl]ClO4. |
|
✖ |
|
Preparation and X-ray Structure of a Catecholato Copper(II) Complex with a Schönberg Adduct. |
|
✖ |
|
Synthesis, structure and catalase-like activity of Cu(N-baa)2(phen) (phen = 1,10-phenanthroline, N-baaH = N-benzoylanthranilic acid). |
|
✖ |
Pages
Chapitres d'ouvrages (2)
| Reference | Résumé graphique | HAL |
|---|---|---|
|
A. Jalila Simaan, Alda Lisa Concia, Alessia Munzone, Maria-Chrysanthi Kafentzi, Amélie Kochem, et al.. Modeling the Mononuclear Copper Monooxygenase Active Site. Series on Chemistry, Energy and the Environment: Volume 5 Bioinspired Chemistry; From Enzymes to Synthetic Models, pp.185-263, 2019, ⟨10.1142/9789813274440_0008⟩. ⟨hal-02094996⟩ |
|
✖ |
|
A. Jalila Simaan, Marius Réglier. CHAPTER 20. 1-Aminocyclopropane-1-Carboxylic Acid Oxidase. 2-oxoglutarate-dependent oxygenases RSC Metallobiology Series, 3., pp.425-437, 2015, ⟨10.1039/9781782621959-00425⟩. ⟨hal-02095042⟩ |
|
✖ |