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Dr.
 
Xavier
 
BUGAUT

Portrait de Dr. Xavier Bugaut
Dr.
Xavier
BUGAUT
AMU iSm2 service 541
Campus Scientifique de St Jérôme
13397
Marseille cedex 20
FRANCE
Téléphone
Fax
0491 28 9187
Entrée
01/01/2011
Parcours

Since september 2021: Professeur des Universités, Ecole européenne de Chimie, Polymères et Matériaux (ECPM), Strasbourg. We are currently moving to our new location, please check our new website (under contruction) for further information: http://lima.unistra.fr/catorg/

Since 2011: Maître de Conférences (equivalent to assistant professor), Aix Marseille Université, iSm2, team STEREO. Habilitation à Diriger les Recherches defended on January 14th, 2021.

2010-2011: Postdoctoral research associate, Westfälische Wilhelms-Universität Münster, Germany, supervisor: Prof. Dr. Frank Glorius.

2006-2009: PhD in Organic Chemistry, Institut de Chimie des Substances Naturelles (ICSN), Gif-sur-Yvette, France, supervisor: Dr. Emmanuel Roulland.

2006: Master degree training period, Sanofi-Aventis, Vitry-sur-Seine, supervisors: Dr. Arielle Genevois-Borella and Dr. Ingrid Devillers.

2005-2006: Master degree in Chemistry, Université Montpellier II. 2004-2005: One-year training period, Merck KGaA, Darmstadt, Allemagne, supervisor: Dr. Ulrich Emde.

2002-2006: Degree in chemical engineering, with specialization in fine organic chemistry, Ecole Nationale Supérieure de Chimie de Montpellier

Enseignements

Bachelor's degree in Chemistry:

4th semester: reaction mechanisms (coordinator)

 

Master's degree in Chemistry:

8th semester: pericyclic reactions and stereoelectronic effets

8th semester: experimental projects

9th semester: advanced organocatalysis

 

Selective and multidisciplinary Bachelor's degree co-habilitated by Ecole Centrale Marseille in Mathematics-Physics-Chemistry-Informatics (MPCI):

1st semester: introduction to organic chemistry (representation of molecules, nomenclature, stereochemistry)

3rd semester: reaction mechanisms

Thématiques

. Enantioselective Organocatalysis

- Synthesis and Use of Original 1,3-Dicarbonyl Compounds

- Enantioselective Multicomponent Reactions

- Halogen-Bonding Organocatalysis

- Synthesis of Axially Chiral Compounds by Central-to-Axial Conversion of Chirality

. Dearomatization of Aromatic compounds

. Total Synthesis of Natural Products

Collaborations et groupes

Current students:

- Antonio Recupido (1st-year PhD student)

- Clément Lemaitre (3rd-year PhD student)

- Chunyang Li (3rd-year PhD student, in collaboration with Prof. Alexandre Martinez and Dr. Bastien Chatelet)

- Dr. Mouhamadou Fofana (exchange PhD student, Prof. Ibrahima Ndiaye, Université Cheikh Anta Diop, Dakar, Senegal)

- Dr. Bohdan Biletski (post-doctoral research associate)

Former students:

- David Givaudan (PhD student, 2017-2021)

- Arun Kumar Ramar (post-doctoral research associate, 2019-2020 // // now post-doctoral research associate at CEA Saclay)

- Andrea Mambrini (Erasmus student, Università degli Studi di Perugia, Italy)

- Dr. Karthik Devaraj (post-doctoral research associate, 2018-2019 // now post-doctoral research associate with Prof. Cathleen Crudden, Queen's University, Kingston, Canada)

- Dr. Nicolas Dalmasso (post-doctoral research associate, 2017-2018 // now research chemist at Charnwood Molecular, Loughborough, UK )

- Hizia Chérif (Master student // now PhD student, Institut de Chimie radicalaire, Aix-Marseille Université)

- Pablo Romo Valdés (exchange PhD student, Prof. Jairo Quiroga Puello, Universidad del Valle, Cali, Colombia)

- Antonio Puglisi (exchange PhD student within the Erasmus programm, 2017, Prof. Marco Bella, La Sapienza Universita, Rome, Italy)

- Dr. Tanguy Saget ( post-doctoral research associate, 2016-2017 // then post-doctoral research associate with Prof. Burkhard König, Universität Regensburg, Germany // now CNRS researcher at the Institut de Chimie des Substances Naturelles, Gif-sur-Yvette)

- Dr. Yohan Dudognon (PhD student, 2013-2016 // then post-doctoral research associate with Prof. Alois Fürstner, Max-Planck-Institut für Kohlenforschung, Mülheim-an-der-Ruhr, Germany // now chemist at Aroma Sense, Marseille)

- Dr. Ophélie Quinonero (PhD student, 2013-2016 // then post-doctoral research associate with Prof. Antonio Echavarren, ICIQ, Tarragona, Spain // now medicinal chemist at Oxeltis, Montpellier)

- Ronan Rocaboy (Master student, 2015 // then PhD student with Prof. Olivier Baudoin, University of Basel, Switzerland // non post-doctoral research associate with Prof. Matthias Wymann at University of Basel, Switzerland)

- Dr. Haiying Du (PhD student, 2011-2014 // now assistant professor at the School of Environment, Chengdu University of Technology, China)

- Juan Martin Lopez (Master student, 2013)

- Dr. Maria del Mar Sanchez Duque (post-doc, 2012 // now sustainable development project manager, Clinique Pasteur, Toulouse)

Remerciements

The following institutions and companies are acknowledged for their financial support to our research activities:

- Aix Marseille Université

- Centre National de la Recherche Scientifique (CNRS)

- Agence Nationale de la Recherche (ANR) : ANR-19-CE07-0029-01 (Bond-X-Bond)

- A*MIDEX (Aix Marseille Université's excellence initiative) : A-M-AAP-EI-17-150-170301-11.01-BUGAUT-SAT (CDD)

- Provence-Alpes-Côte d'Azur region : ERC Booster 2018 (InterconvCat)

- Chinese Scolarship Council

- Janssen Cilag

- Provepharm

Responsabilités administratives

. Selective and multidisciplinary Bachelor's degree co-habilitated by Ecole Centrale Marseille in Mathematics-Physics-Chemistry-Informatics (MPCI):

-co-coordinator of the Bachelor's degreee

-coordinator of chemistry teaching over the three year of the Bachelor degree

-coordination of all teaching during the second year

. Coordination of STeRéO-group seminars

Publications (30)
Reference Résumé graphique HAL

Hemicryptophane Cages with a C 1 -Symmetric Cyclotriveratrylene Unit

Chunyang Li, Anne-Doriane Manick, Marion Jean, Muriel Albalat, Nicolas Vanthuyne, Jean-Pierre Dutasta, Xavier Bugaut, Bastien Chatelet, Alexandre Martinez, Journal of Organic Chemistry, 2021, 86, 15055-15062. <hal-03516854>

The Chloroazaphosphatrane Motif for Halogen Bonding in Solution

Chunyang Li, Anne-Doriane Manick, Jian Yang, David Givaudan, Bohdan Biletskyi, Sabine Michaud-Chevalier, Jean-Pierre Dutasta, Damien Hérault, Xavier Bugaut, Bastien Chatelet, Alexandre Martinez, Inorganic Chemistry, 2021, 60, 11964-11973. <hal-03516842>

On the Enantioselective Phosphoric-Acid-Catalyzed Hantzsch Synthesis of Polyhydroquinolines

Ophélie Quinonero, Clément Lemaitre, Marion Jean, Nicolas Vanthuyne, Christian Roussel, Damien Bonne, Thierry Constantieux, Cyril Bressy, Xavier Bugaut, Jean Rodriguez, Organic Letters, 2021, 23, 3394-3398. <hal-03285117>

Azaphosphatranes Catalyzed Strecker Reaction in the Presence of Water

Jian Yang, Anne-Doriane Manick, Chunyang Li, Xavier Bugaut, Bastien Chatelet, Véronique Dufaud, Damien Hérault, Alexandre Martinez, ChemistrySelect, 2020, 5, 14764-14767. <hal-03180316>

Enantioselective Organocatalyzed Michael Additions of Nitroalkanes to 4-Arylidenedihydrofuran-2,3-diones and 4-Arylidenepyrrolidine-2,3-diones

Mouhamadou Fofana, Yohan Dudognon, Laura Bertrand, Thierry Constantieux, Jean Rodriguez, Ibrahima Ndiaye, Damien Bonne, Xavier Bugaut, European Journal of Organic Chemistry, 2020, 2020, 3486 - 3490. <hal-03163964>

Weinreb β-Ketoamides in Enantioselective Organocatalysis: A Balance between Reactivity and Selectivity

Haiying Du, Yohan Dudognon, Jean Rodriguez, Thierry Constantieux, Xavier Bugaut, SYNLETT, 2018. <hal-01723120>

Organocatalytic Enantioselective Synthesis of Tetrahydropyridines

Yohan Dudognon, Jean Rodriguez, Thierry Constantieux, Xavier Bugaut, European Journal of Organic Chemistry, 2018, 2018, 2432-2442. <hal-01969953>

Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy

Vivek S Raut, Marion Jean, Nicolas Vanthuyne, Christian Roussel, Thierry Constantieux, Cyril Bressy, Xavier Bugaut, Damien Bonne, Jean Rodriguez, Journal of the American Chemical Society, 2017, 139, 2140-2143. <hal-01533761>

Organocatalytic Multicomponent Reactions of 1,3-Dicarbonyls for the Synthesis of Enantioenriched Heterocycles

Haiying Du, Yohan Dudognon, M. del Mar Sanchez Duque, Sébastien Goudedranche, Damien Bonne, Jean Rodriguez, Xavier Bugaut, Thierry Constantieux, SYNTHESIS, 2016, 48, 3479-3503. <hal-01415048>

From Simple Cyclic 1,3-Ketoamides to Complex Spirolactams by Supported Heterogeneous Organocatalysis with PS-BEMP

Aouicha Benmaati, Hadjira Habib Zahmani, Salih Hacini, José Carlos Menéndez, Xavier Bugaut, Jean Rodriguez, Thierry Constantieux, SYNTHESIS, 2016, 48, 3217 - 3231. <hal-01415069>

Pages

Chapitres d'ouvrages (5)
Reference Résumé graphique HAL

Adrien Quintard, Xavier Bugaut, Thierry Constantieux. L'éco-conception, un défi pour la recherche fondamentale . Yvette Lazzeri, Dominique Bonet Fernandez & Mariane Domeizel. Economie circulaire et territoires, Presses universitaires d'Aix-Marseille, pp.133-137, 2017, 979-10-320-0097-7. ⟨hal-01533756⟩

Benzoin and Aza-Benzoin

Xavier Bugaut, In: Gary A. Molander and Paul Knochel (eds.), Comprehensive Organic Synthesis, 2nd Edition, Vol 1, Oxford: Elsevier, 2014, pp.424-470.

1,3-Dicarbonyls in Multicomponent Reactions

X. Bugaut, T. Constantieux, Y. Coquerel, J. Rodriguez, In Multicomponent Reactions in Organic Synthesis, Eds.: J. Zhu, Q. Wang, M.-X. Wang, Wiley-VCH, Weinheim, 2014, Chap. 5, pp 109-158.

Xavier Bugaut, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez. 1,3-Dicarbonyls in Multicomponent Reactions. J. Zhu, Q. Wang, M.-X. Wang. Multicomponent Reactions in Organic Synthesis, Wiley-VCH, Weinheim, pp.109-158, 2014, 978-3-527-33237-3. ⟨hal-01133604⟩

Xavier Bugaut. Benzoin and aza-benzoin. Gary A. Molander and Paul Knochel. Comprehensive Organic Synthesis, 2nd Edition, Elsevier, pp.424-470, 2014, ⟨10.1016/B978-0-08-097742-3.00118-X⟩. ⟨hal-01066271⟩