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Dr.
 
Laetitia
 
SHINTU

Portrait de Dr. Laetitia Shintu
Dr.
Laetitia
SHINTU
AMU iSm2 Service 512
Campus Scientifique de St Jérôme
13397
Marseille cedex 20
Téléphone
Parcours

2002-2006 : Doctorat en physico-chimie et spectrométries moléculaires, Université Paul cezanne, Marseille, France
2005-2006 : ATER en chimie physique, Université Paul Cezanne, Marseille, France
2006-2008 : Postdoctorat à Institute of Food Research, Norwich, UK (Dr I. Colquhoun)
2008-2009 : Postdoctorat à l’ENS de Lyon, Villeurbanne, France (Pr. Lyndon Emsley)
2009 : Maître de Conférence/ Chaire CNRS en RMN et Métabolomique, Université Paul Cézanne, Marseille, France

Enseignements

- Licence : chimie inorganique (TD et TP)
- Master 2 : Analyse de données (Cours)

Thématiques

Métabolomique / Métabonomique
2012-2015 : ANR JCJC IMAPIST (porteur de projet) : Une approche Metabolomique multi-analytique et multi-compartimentée innovante préservant l'intégrité de tous les types d'échantillons (projet ANR-2011- JS08-014-01)

Responsabilités administratives

Début

Publications (30)
Reference Résumé graphique HAL

The coenzyme A precursor pantethine enhances antitumor immunity in sarcoma

Richard Miallot, Virginie Millet, Anais Roger, Romain Fenouil, Catherine Tardivel, Jean-Charles Martin, Fabrice Tranchida, Laetitia Shintu, Paul Berchard, Juliane Sousa Lanza, Bernard Malissen, Sandrine Henri, Sophie Ugolini, Aurélie Dutour, Pascal Finetti, François Bertucci, Jean-Yves Blay, Franck Galland, Philippe Naquet, Life Science Alliance, 2023, 6, e202302200. <hal-04374222>

An essential role of the reversible electron-bifurcating hydrogenase Hnd for ethanol oxidation in Solidesulfovibrio fructosivorans

Arlette Kpebe, Chloé Guendon, Natalie Payne, Julien Ros, Manel Khelil Berbar, Régine Lebrun, Carole Baffert, Laetitia Shintu, Myriam Brugna, Frontiers in Microbiology, 2023, 14, 1139276. <hal-04071158>

Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis

Virginie Millet, Thomas Gensollen, Michael Maltese, Melanie Serrero, Nathalie Lesavre, Christophe Bourges, Christophe Pitaval, Sophie Cadra, Lionel Chasson, Thien Phong Vu Man, Marion Masse, Juan Jose Martinez-Garcia, Fabrice Tranchida, Laetitia Shintu, Konrad Mostert, Erick Strauss, Patricia Lepage, Mathias Chamaillard, Achille Broggi, Laurent Peyrin-Biroulet, Jean-Charles Grimaud, Philippe Naquet, Franck Galland, BMJ - British Medical Journal, 2022. <hal-03975895>

The electron-bifurcating FeFe-hydrogenase Hnd is involved in ethanol metabolism in Desulfovibrio fructosovorans grown on pyruvate

Natalie Payne, Arlette Kpebe, Chloé Guendon, Carole Baffert, Julien Ros, Régine Lebrun, Yann Denis, Laetitia Shintu, Myriam Brugna, Molecular Microbiology, 2022. <hal-03548887>

NMR-based metabolomic analysis of the physiological role of the electron-bifurcating FeFehydrogenase Hnd in Solidesulfovibrio fructosivorans under pyruvate fermentation

Natalie Payne, Arlette Kpebe, Chloé Guendon, Carole Baffert, Matthieu Maillot, Typhaine Haurogné, Fabrice Tranchida, Myriam Brugna, Laetitia Shintu, Microbiological Research, 2022, 268, 127279. <hal-04382053>

Evolution of Thermophilic Microbial Communities from a Deep-Sea Hydrothermal Chimney under Electrolithoautotrophic Conditions with Nitrate

Guillaume Pillot, Oulfat Amin Ali, Sylvain Davidson, Laetitia Shintu, Yannick Combet-Blanc, Anne Godfroy, Patricia Bonin, Pierre-Pol Liebgott, Microorganisms, 2021, 9, 2475. <hal-03563636>

Identification of enriched hyperthermophilic microbial communities from a deep-sea hydrothermal vent chimney under electrolithoautotrophic culture conditions

Guillaume Pillot, Oulfat Amin Ali, Sylvain Davidson, Laetitia Shintu, Anne Godfroy, Yannick Combet-Blanc, Patricia Bonin, Pierre-Pol Liebgott, Scientific Reports, 2021, 11. <hal-03427430>

Evaluation of the Rotating-Frame Relaxation ( T 1ρ ) Filter and Its Application in Metabolomics as an Alternative to the Transverse Relaxation ( T 2 ) Filter

Elena Piersanti, Lamya Rezig, Fabrice Tranchida, Wael El-Houri, Seidou Abagana, Mylène Campredon, Laetitia Shintu, Mehdi Yemloul, Analytical Chemistry, 2021, 93, 8746-8753. <hal-03655575>

Fecal Metabolic Profiling of Breast Cancer Patients during Neoadjuvant Chemotherapy Reveals Potential Biomarkers

Oumaima Zidi, Nessrine Souai, Henda Raies, Farhat Ben Ayed, Amel Mezlini, Sonia Mezrioui, Fabrice Tranchida, Jean-Marc Sabatier, Amor Mosbah, Ameur Cherif, Laetitia Shintu, Soumaya Kouidhi, Molecules, 2021, 26, 2266. <hal-03358035>

Targeting Mitochondrial Complex I Overcomes Chemoresistance in High OXPHOS Pancreatic Cancer

Rawand Masoud, Gabriela Reyes-Castellanos, Sophie Lac, Julie Garcia, Samir Dou, Laetitia Shintu, Nadine Abdel Hadi, Tristan Gicquel, Abdessamad El Kaoutari, Binta Diémé, Fabrice Tranchida, Laurie Cormareche, Laurence Borge, Odile Gayet, Eddy Pasquier, Nelson Dusetti, Juan Iovanna, Alice Carrier, Cell Reports Medicine, 2020, 1, 100143. <hal-03097443>

Pages

Communications orales et par affiche (7)
Reference Résumé graphique HAL

Afef Cherni, Elena Piersanti, Sandrine Anthoine, Caroline Chaux, Laetitia Shintu, et al.. Challenges in the decomposition of 2D NMR spectra of mixtures of small molecules. Faraday Discussion Meeting, May 2019, Edinburgh, United Kingdom. ⟨hal-02371045⟩

A Masion, Laetitia Shintu, Catherine Santaella. Ecotoxicity of manufactured Al nanophases. 253rd ACS National Meeting, Apr 2017, San Francisco, CA, United States. ⟨hal-03547448⟩

Jean-Charles Martin, Mathieu Maillot, Gerard Mazerolles, Alexandre Verdu, Bernard Lyan, et al.. Can we Trust Untargeted Metabolomics: Results of the Metabo-ring Initiative, a Large-scale Multi-instruments Inter-laboratoire Study. 9. Annual Conference of the Metabolomics Society, Jul 2013, Glasgow, United Kingdom. 2013, 9th Annual Conference of the Metabolomics Society. ⟨hal-01123136⟩

Alexandre Verdu, Bernard Lyan, Carole Migné, Catherine Defoort, Cécile Canlet, et al.. Can we trust untargeted metabolomics: results of the metabo-ring study. 2. African-European Conference on Chemometrics - Afrodata 2012, Nov 2012, Stellenbosch, South Africa. ⟨hal-01595486⟩

Alexandre Verdu, Bernard Lyan, Carole Migné, Catherine Defoort, Cécile Canlet, et al.. Can we trust untargeted metabolomics: first results of the metabo-ring study. 8. Annual International Meeting of the Metabolomics Society, Jun 2012, Washington, United States. , 2012. ⟨hal-01595487⟩

Alexandre Verdu, Bernard Lyan, Carole Migné, Catherine Defoort, Cécile Canlet, et al.. Peut-on faire confiance à la métabolomique: résultats de l'initiative MetaboRing. 6. Journées Scientifiques du Réseau Français de Métabolomique et Fluxomique (RFMF), May 2012, Nantes, France. ⟨hal-01594993⟩

Benjamin J. Blaise, Cécile Vercherat, V. Navratil, Annie Lacheretz-Bernigaud, Laetitia Shintu, et al.. Statistical recoupling of variables for the identification of candidate biomarkers and perturbed metabolic networks. Application to whole organism NMR. 7th International Conference of the Metabolomics Society, Jun 2011, Cairns, Australia. ⟨hal-00980051⟩