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Dr. Nicolas Vanthuyne's picture
AMU iSm2 Service 432
Campus Scientifique de St Jérôme
Marseille cedex 20
Phone number

Career path

2004 Doctorat de chimie organique (Université “Paul Cézanne”, Aix-Marseille III)
2000 Ingénieur ENSSPICAM (Ecole Nationale Supérieure de Synthèses, de Procédés et d'Ingénierie d'Aix-Marseille) et Diplôme d’Etudes Approfondies de Chimie et Physico-Chimie Moléculaire Organique (Université “Paul Cézanne”, Aix-Marseille III)

Research themes

Séparations analytiques et préparatives d’énantiomères par chromatographie liquide chirale
Stéréochimie dynamique

Publications (247)
Reference Graphical abstract HAL

Synthesis, Chiral Separation, and Absolute Configuration of Bis-(N-aryl) Atropisomeric Triads: 1,2-Bis-[4-methyl-2-(thi)oxo-2,3-dihydrothiazol-3-yl]-benzene.

C. Roussel,, S. Kaid-, A. Radia, Federico, M. Renaudin,., N. Vanthuyne, Chirality 2009, 21:160-166

Synthesis, Structural Analysis, and Chiral Investigations of Some Atropisomers with EE-Tetrahalogeno-1,3-butadiene Core.

F. Piron, N. Vanthuyne, B. Joulin, J.-V. Naubron , C. Cismas , A. Terec , R.A. Varga , C. Roussel , J. Roncali, I. Grosu, J. Org. Chem.2009, 74, (23), 9062-9070.

New Selective Phosphodiesterase 4D Inhibitors Differently Acting on Long, Short, and Supershort Isoforms.

O. Bruno, A. Romussi, A. Spallarossa, C. Brullo, S. Schenone, F. Bondavalli, N. Vanthuyne, C. Roussel, Journal of Medicinal Chemistry 2009, 52: 6546-6557.

Proteases screening for the kinetic resolution of amines with N-acyl ??amino acid trifluoromethyl esters. Automated docking approach of binding energies using Subtilisin Novo as prototype for serine proteases

A.-L. Bottalla, S. Queyroy, N. Azzi-Schue, N. Vanthuyne, S.Gastaldi, M. P. Bertrand, G. Gil, Tetrahedron : Asymmetry. 2009, 20, 2823-2834

Synthesis of Some Novel Organic Nitrates and Comparative in Vitro Study of Their Vasodilator Profile.

K. Chegaev, L. Lazzarato, P. Marcarino, A. Di Stilo, R. Fruttero, N. Vanthuyne, C. Roussel, A. Gasco, Journal of Medicinal Chemistry, 2009, 52: 4020-4025.

Synthesis of (+)-striatene: confirmation of its stereostructure

Paul Bremond, Nicolas Vanthuyne, Gerard Audran, Tetrahedron Letters, 2009, 50, 5723-5725. <hal-02516295>

Novel chromatographic resolution of chiral diacylgkycerols and analysis of the stereoselective hydrolysis of triacylglycerols by lipases

J. A. Rodriguez, L. D. Mendoza, F. Pezotti, N. Vanthuyne, J. Leclaire, R. Verger, G. Buono, F. Carriere, F. Fotiadu Analytical Biochemistry 2008, 375, 196-208

Atropisomerism in the 2-Arylimino-N-(2-hydroxyphenyl)thiazoline Series: Influence of Hydrogen Bonding on the Racemization Process.

C. Roussel,, N. Vanthuyne, M. Bouchekara,, A. Djafri, J. Elguero,, I. Alkorta, Journal of Organic Chemistry 2008, 73, 403-411.

Highly efficient photochemically induced thiyl radical-mediated racemization of aliphatic Amines at 30 degrees C.

L. Routaboul, N. Vanthuyne, S. Gastaldi, G. Gil, M.P. Bertrand, J. Org. Chem. 2008, 73: 364-368.

Photochemically Induced Thiyl Radical-Mediated Racemization of Aliphatic Amines

L. Routaboul, N. Vanthuyne, S.Gastaldi, G. Gil and M.Bertrand, , J. Org. Chem., 2008, 73, 364 - 368


Oral or poster communication (3)
Reference Graphical abstract HAL

Kais Dhbaibi, Monika Srebro-Hooper, Philippe Blanchard, Clément Cabanetos, Nicolas Vanthuyne, et al.. Design d’émetteurs hélicèniques pour l’élaboration d’OLEDs chirales. Science et Technologie des systèmes Pi-Conjugués (SPIC), Oct 2019, Arras, France. ⟨hal-02922011⟩

Cécile Mézière, Magali Allain, Cristina Oliveras-Gonzalez, Thomas Cauchy, Nicolas Vanthuyne, et al.. Tetrathiafulvalene-[2.2]paracyclophanes: Synthesis, chiral structures and chiroptical properties. Journées André Collet de la Chiralité, 2018, Noirmoutier, France. 2018. ⟨hal-02564566⟩

Ludovic Favereau, Monika Srebro-Hooper, Francesco Zinna, Philippe Blanchard, Clément Cabanetos, et al.. Matériaux moléculaires chiraux pour l'optoélectronique. SPIC 2017, Oct 2017, Limoges, France. ⟨hal-02888985⟩

Chapters of books (2)
Reference Graphical abstract HAL

Nicolas Vanthuyne, Christian Roussel. Chiroptical Detectors for the Study of Unusual Phenomena in Chiral Chromatography. Topics in Current Chemistry, Differentiation of Enantiomers I, pp.107-151, 2013, ⟨10.1007/128_2013_441⟩. ⟨hal-02528021⟩

Ibon Alkorta, José Elguero, Christian Roussel, Nicolas Vanthuyne, Patrick Piras. Atropisomerism and Axial Chirality in Heteroaromatic Compounds. Advances in Heterocyclic Chemistry, 105, pp.1-188, 2012, ⟨10.1016/B978-0-12-396530-1.00001-2⟩. ⟨hal-02517553⟩