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Prof. Jean Rodriguez's picture
AMU iSm2 Service 531
Campus Scientifique de St Jérôme
Marseille cedex 20
Phone number
0491 28 9187
Date of entry
Career path

1984 : PhD of Speciality at the University of Aix-Marseille
1984 : Recruted by the CNRS as Attaché de Recherche
1987 : PhD in Sciences at the University of Aix-Marseille
1988 : Postdoctoral reseach associate, University of California (Berkeley), supervisor: Prof K.P.C. Vollhardt
1989 : Promoted Chargé de Recherche de 1ère classe at CNRS
1992 : Habilitation at the University of Aix-Marseille
1998 : Promoted Directeur de Recherche at the CNRS
2002 : Nominated full Professor at the University of Aix-Marseille


1998 : Prize from ACROS-French Chemical Society in organic chemistry
2009 : Prize from the Société Chimique de France, Division Chimie Organique
2013 : Member of the Editorial Board of European Journal of Organic Chemistry
2013 : Distinguished Senior Member of the Société Chimique de France
2021 : Grand Prix de l'Académie des Sciences Emile Jungfleisch


Bachelor Degree in Chemistry
*Ionic and Polar Rearrangements in Organic Synthesis

Master Degree in Chemistry
*Strategies in Synthetic Organic Chemistry (Retrosynthetic analysis, Total synthesis, Protection and Deprotection of functional groups)
*New Selective Multiple Bond-Forming Transformations (Metallo- and Organocatalyzed Consecutive, Domino and Multicomponent reactions)
*Recent Applications of enantioselective metallo- and organocatalysis in Organic Synthesis

Collaborations and groups

Dr Muriel AMATORE, Assitant Professor
Dr Damien BONNE, Assistant Professor
Dr Xavier BUGAUT, Full professor
Dr Thierry CONSTANTIEUX, Full Professor
Dr Yoann COQUEREL, Associate Researcher from the CNRS
Dr Adrien QUINTARD, Associate Researcher from the CNRS
Dr. Manuel BARDAY, Postdoctoral Research Associate (2022)
Dr. Expédite Yen-PON, Postdoctoral Research Associate (2022)
Pierre BOUILLAC, PhD student (2019-2022)
Birane DIOP, PhD student (2022)
Arthur GAUCHERAND, PhD student (2020-2023)
Na SHAO, PhD student (2020-2024)

Administrative responsabilities

1999-2007 : Member of Bureau National de la S F C, Division Chimie Organique
2000-2006 : Expert auprès du ministère dans le cadre de la MSTP4
2004-2007 : Director of the Reseach Unit SYMBIO
2006-2011 : Chargé de Mission à l'Institut de chimie du CNRS (section 12)
2008- Present : Director of the Institut des Sciences Moléculaires de Marseille (iSm2)       

Publications (210)
Reference Graphical abstract HAL

Selective transformations of b-ketoesters promoted by Dowex basic ion-exchange resins.

C. SIMON, J. F. PEYRONEL, F. CLERC, J. RODRIGUEZ Eur. J. Org. Chem. 2002, 3359-3364.

A New Multicomponent Domino Transformation of 1,3-Dicarbonyl Compounds: One-Pot regio-, Chemo- and Stereoselective Access to Valuable a,g-Difunctionalized a-ketoesters and amides.

H. Habib-Zahmani, S. Hacini, E. Charonnet, J. Rodriguez Synlett, 2002, 1827-1831.

One-pot Michael addition-intramolecular carbocyclization of dimethyl propargyl-malonate with nitroalkenes : a new stereoselective [3+2] annulation to 1-nitro 2-methylenecyclopentanes.

M. GUILLAUME, E. DUMEZ, J. RODRIGUEZ, J. P. DULCERE Synlett, 2002, 1883-1886.

Novel DBU-MeOH Promoted One-Pot Stereoselective g-Functionalization of 1,3-Dicarbonyls : An easy access to g-Arylidene, g-Alkylidene and g-Allylidene a-keto-esters and -amides.

E. CHARONNET, M. H. FILIPPINI, J. RODRIGUEZ Synthesis 2001, 788.

Highly Efficient Phosphazene Base-Catalyzed Michael Addition of b-Ketoesters in Water.

D. BENSA, J. M. BRUNEL, G. BUONO, J. RODRIGUEZ Synlett, 2001, 5, 715-717.

A New Multicomponent Domino Reaction of 1,3-Dicarbonyl Compounds : One-Pot Access to Polycyclic N/O-, N/S-, and N/N-Aminals.

C. SIMON, J. F. PEYRONEL, J. RODRIGUEZ Org. Lett. 2001, 3, 2145.

C-C versus C-O Anionic Domino Cycloalkylation of Stabilized Carbanions. Facile One-Pot Stereoselective Preparation of Functionalized Bridged Bicycloalkanones and Cyclic Enol Ethers.


Nouvelles réactions domino anioniques utilisant la réactivité d'anions stabilisés.

J. RODRIGUEZ L'Actualité Chimique 2000, 6, 64.

Intramolecular 6-exo Cyclization of 1-Nitro-6-heptenyl Radicals Generated by One-Electron Oxidation of Aci-Nitroanions with CAN : A Completely Stereoselective Formation of 2,3,4-Trisubstituted Tetrahydropyrans.

A. C. DURAND, J. RODRIGUEZ, J. P. DULCERE Synlett. 2000, 731-733.

The Cohalogenation of 1-N-Vinylpyrimidinediones. A New Approach to Nucleosides Analogs.

N. BARET, J. P. DULCERE, J. RODRIGUEZ, J. M. -PONS, R. FAURE Eur. J. Org. Chem. 2000, 1507-1516.


Books (3)
Reference Graphical abstract HAL

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

Eds.: J. Rodriguez, D. Bonne, John Wiley & Sons, Inc., Hoboken, NJ, USA, 2015.

Jean Rodriguez, Damien Bonne. Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis. John Wiley & Sons, 2015, 978-1-118-67271-6. ⟨hal-01323433⟩


David Pierrot, Damien Bonne, Jean Rodriguez 2014, e-EROS Encyclopedia of Reagents for Organic Synthesis. 1–5.

Chapters of books (9)
Reference Graphical abstract HAL

Yoann Coquerel, Jean Rodriguez. The Wolff Rearrangement: Tactics, Strategies and Recent Applications in Organic Synthesis. Molecular Rearrangements in Organic Synthesis, Johne Wiley & Sons, pp.59-84, 2015, 978-1-118-34796-6. ⟨hal-01224316⟩

1,3-Dicarbonyls in Multicomponent Reactions

X. Bugaut, T. Constantieux, Y. Coquerel, J. Rodriguez, In Multicomponent Reactions in Organic Synthesis, Eds.: J. Zhu, Q. Wang, M.-X. Wang, Wiley-VCH, Weinheim, 2014, Chap. 5, pp 109-158.

Xavier Bugaut, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez. 1,3-Dicarbonyls in Multicomponent Reactions. J. Zhu, Q. Wang, M.-X. Wang. Multicomponent Reactions in Organic Synthesis, Wiley-VCH, Weinheim, pp.109-158, 2014, 978-3-527-33237-3. ⟨hal-01133604⟩

Reactions Involving an alpha,beta-Unsaturated Compound as Electrophilic Component with the Michael Addition as the Key Step

J. Rodriguez, D. Bonne, Y. Coquerel, T. Constantieux, dans 'Multicomponent Reactions 2', 'Science of Synthesis Reference Library', T. J. J. Müller, Ed., Thieme, Stuttgart, 2013, Chap. 2.1.1, p. 1-36.

Stereoselective Multicomponent Reactions: from Simple 1,3-Dicarbonyls to Functionalized Chiral Heterocycles

D. Bonne, Y. Coquerel, T. Constantieux, J. Rodriguez in Targets in Heterocyclic Systems - Chemistry and Properties, Vol. 15, Eds.: O. A. Attanasi, D. Spinelli, Societa? Chimica Italiana, Roma, 2011, pp. 140-163. 

Utilisation des dérivés 1,3-dicarbonylés dans les réactions domino et multicomposé

Damien Bonne, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez Techniques de l'Ingénieur 2010, CHV2210

Damien Bonne, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez. Utilisation des dérivés 1,3-dicarbonylés dans les réactions domino et multicomposé. Ideas in Chemistry and Molecular Sciences: Advances in Synthetic Chemistry, pp.CHV2210, 2010. ⟨hal-00680619⟩

Yoann Coquerel, Thomas Boddaert, Marc Presset, Damien Mailhol, Jean Rodriguez. Multiple Bond-Forming Transformations: the Key Concept towards Eco-compatible Synthetic Organic Chemistry. Ideas in Chemistry and Molecular Sciences, Vol.1 Advances in synthetic chemistry, Wiley-VCH, Weinheim, pp.187-202, 2010, 3527325395. ⟨hal-00681017⟩

Maria del Mar Sanchez Duque, Christophe Allais, Nicolas Isambert, Thierry Constantieux, Jean Rodriguez. beta-diketo building blocks for MCRs-based syntheses of heterocycles. Topics in Heterocyclic Chemistry, Springer, pp.227-277, 2010, ⟨10.1007/7081_2010_26⟩. ⟨hal-00680508⟩

Patents (1)
Reference Graphical abstract HAL

Adrien Quintard, Céline Sperandio, Jean Rodriguez. NOVEL FLUORINATED POLYOLS AND THEIR USE AS ORGANOGELATORS. France, Patent n° : WO/2019/238582. 2019. ⟨hal-02878986⟩