Institut des Sciences Moléculaires de Marseille Université Paul cézanne Aix Marseille III
               
       

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Jean Rodriguez

Prof. Jean RODRIGUEZ

AMU iSm2 Service 531
Campus Scientifique de St Jérôme
13397 Marseille cedex 20

 

Phone : 0491 28 8933

Fax : 0491 28 9187

E-Mail : jean.rodriguez{noSPAM}univ-amu.fr

 

Career

1984 : PhD of Speciality at the University of Aix-Marseille
1984 : Recruted by the CNRS as Attaché de Recherche
1987 : PhD in Sciences at the University of Aix-Marseille
1988 : Postdoctoral reseach associate, University of California (Berkeley), supervisor: Prof K.P.C. Vollhardt
1989 : Promoted Chargé de Recherche de 1ère classe at CNRS
1992 : Habilitation at the University of Aix-Marseille
1998 : Promoted Directeur de Recherche at the CNRS
2002 : Nominated full Professor at the University of Aix-Marseille

Honors

1998 : Prize from ACROS-French Chemical Society in organic chemistry
2009 : Prize from the Société Chimique de France, Division Chimie Organique
2013 : Member of the Editorial Board of European Journal of Organic Chemistry
2013 : Distinguished Senior Member of the Société Chimique de France
2013 : Dr Paul Janssen invited lecturer, Beerse (Belgium)

Teaching

Bachelor Degree in Chemistry
*Ionic and Polar Rearrangements in Organic Synthesis

Master Degree in Chemistry
*Strategies in Synthetic Organic Chemistry (Retrosynthetic analysis, Total synthesis, Protection and Deprotection of functional groups)
*New Selective Multiple Bond-Forming Transformations (Metallo- and Organocatalyzed Consecutive, Domino and Multicomponent reactions)
*Recent Applications of enantioselective metallo- and organocatalysis in Organic Synthesis

Research Topics

Selective Functionalization of Olefins
* Allylvinyl ethers
* Methylene butyrolactones
* Synthesis and Structural Modifications of nucleosides

New synthetic applications of Michael addition and Carroll rearrangement
* Study of the Stereoselectivity
* Synthesis of the Prelog-Djerassi lactone
* Synthesis and Reactivity of Bridged Bicyclic Systems
* Development of the aqueous versions

New Domino Multicomponent Reactions Involving Stabilized Carbanions
* gama-Arylidenation of 1,3-Dicarbonyls
* Ring Expansions: New Acces to Functionalized Cycloheptanes and Cyclooctanes
* Stereoselective Heterocyclizations (4- and 7-Azaindoles, Benzimidazoles, Triazoles, Pyridines, Pyrolidones, Pyrrolopiperazines, Diazepines,  Diazabicyclooctanes, Oxazinones, Pyrazolidinones, Spiroglutarimides,  Fluoro-Pyrimidines, Spirooxindoles, Spirolactams, Benzodiazepinones, Furans, Dihydrofurans)
* Stereoselective Cyclopentannulations with nitroolefins
* New Developements of the Chemistry of Arynes (Selective C-Arylation, C-H Bond Functionalization)

New Developments of Heterogeneous and Homogeneous Catalysis
* New Multicomponent Reactions
* Palladium-Catalyzed Rearrangements
* Domino Metathesis of functionalized Olefins and Enynes (Bridged carbocyclic derivatives, Tetrahydro-furans and Pyrans)
* Functionalized N-Heterocyclic Carbenes for the Catalysis of Michael Additions

New Developments of Microwave Activation Toward Eco-compatible Synthetic Methodologies
* Activation of Cross-Metathesis
* Selective Synthesis of Functionalized 1,3-Dicarbonyls
* New developments of the Chemistry of alpha-Oxo Ketenes
* Stereoselective Spirocyclizations

New Developments of Enantioselective Organocatalysis
* Enantioselective Cyclopentannulations with nitroolefins 
* Enantioselective Michael Addition Involving 1,2- and 1,3-Dicarbonyls: Synthetic and Mechanistic investigations
* Enantioselective Domino Reactions Involving 1,2- and 1,3-Dicarbonyls
* Enantioselective Multicomponent Reactions (Diazabicyclooctanes, Pyrrolopiperazines)
* Enantioselective Heterocyclizations (Spiroaminals, Spiroglutarimides)
* Enantioselective Synthesis of Heterobiaryl Derivatives
* Enantioselective Dual Organic and Organometallic Catalysis (Functionalization of Allylic Alcohols)
* Total Synthesis of Natural Products (Isishippuric Acid, Speciophyllin)

Associate Collaborators and Group

Dr Damien BONNE, Assistant Professor
Dr Xavier BUGAUT, Assistant Professor
Dr Thierry CONSTANTIEUX, Full Professor
Dr Yoann COQUEREL, Associate Researcher from the CNRS
Dr Adrien QUINTARD, Associate Researcher from the CNRS
Dr Vivek RAUT, Postdoctoral Reseach Associate (2013-2016)
Mylène ROUDIER, PhD student (2013-2016)
Fabien PEREZ, PhD student (2013-2016)
Ophélie QUINONERO, PhD student (2013-2016)
Yohan DUDOGNON, PhD student (2013-2016)
Cecilia SASSO D'ELIA PhD student (2014-2017)
Yun-Long WEI PhD student (2015-2018)
Jessica Orrego-Hernandez short-stay PhD Student (2016)

Administrative responsibilities

1999-2007 : Member of Bureau National de la S F C, Division Chimie Organique
2000-2006 : Expert auprès du ministère dans le cadre de la MSTP4
2004-2007 : Director of the Reseach Unit SYMBIO
2006-2011 : Chargé de Mission à l'Institut de chimie du CNRS (section 12)
2008- Present : Director of the Institut des Sciences Moléculaires de Marseille (iSm2)       

Publications and links to the editor

Some pdf files of our publications are available on the open archive website HAL
Title - Authors - Journal
Graphical Abstracts
Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy

Vivek S. Raut, Marion Jean, Nicolas Vanthuyne, Christian Roussel, Thierry Constantieux, Cyril Bressy, Xavier Bugaut, Damien Bonne, and Jean Rodriguez J. Am. Chem. Soc., 2017, 139 (6), 2140?2143

Enantioselective Organocatalyzed Consecutive Synthesis of Alkyl 4,5-Dihydrofuran-2-carboxylates from alpha-Keto Esters and (Z)-beta-Chloro-?-nitrostyrenes

Diana Becerra, Wilfried Raimondi, Daniel Dauzonne, Thierry Constantieux, Damien Bonne, Jean Rodriguez Synthesis 2017, 49(01), 195-201

Organocatalytic Multicomponent Reactions of 1,3-Dicarbonyls for the Synthesis of Enantioenriched Heterocycles

H. Du, Y. Dudognon, M. M. Sanchez Duque, S. Goudedranche, D. Bonne, J. Rodriguez, X. Bugaut, T. Constantieux Synthesis, 2016, 48, 3479-3503.

From Simple Cyclic 1,3-Ketoamides to Complex Spirolactams by Supported Heterogeneous Organocatalysis with PS-BEMP

A. Benmaati, H. Habib Zahmani, S. Hacini, J. C. Menéndez, X. Bugaut, J. Rodriguez, T. Constantieux Synthesis, 2016, 48, 3217-3231.

A switchable dual organocatalytic system and the enantioselective total synthesis of the quadrane sesquiterpene suberosanone

Y. Ren, Marc Presset, Jeremy Godemert, Nicolas Vanthuyne, Jean-Valère Naubron, Michel Giorgi, Jean Rodriguez, and Yoann Coquerel Chem. Commun. 2016, 52, 6565-6568

Time-Efficient Synthesis of Pyrido[2,3-d]pyrimidinones via alpha-Oxoketenes

Juan-Carlos Castillo, Jairo Quiroga, Jean Rodriguez, and Yoann Coquerel Eur. J. Org. Chem. 2016, 1994-1999

Recent Achievements in Enantioselective Borrowing Hydrogen by the Combination of Iron- and Organocatalysis

Mylène Roudier, Thierry Constantieux, Jean Rodriguez, and Adrien Quintard Chimia 2016, 70, 97?101

Addition of Silylated Nucleophiles to ?-Oxoketenes

Y. Dudognon, M. Presset, J. Rodriguez, Y. Coquerel, X. Bugaut, T. Constantieux Chem. Commun. 2016, 52, 3010-3013.

Combining Organocatalysis with Central-to-Axial Chirality Conversion: Atroposelective Hantzsch-Type Synthesis of 4-Arylpyridines

O. Quinonero, M. Jean, N. Vanthuyne, C. Roussel, D. Bonne, T. Constantieux, C. Bressy, X. Bugaut, J. Rodriguez Angew. Chem. Int. Ed. 2016, 55,1401-1405.

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

Eds.: J. Rodriguez, D. Bonne, John Wiley & Sons, Inc., Hoboken, NJ, USA, 2015.

Pseudo-Multicomponent Reactions of Arynes with N?Aryl Imines

Juan-Carlos Castillo, Jairo Quiroga, Rodrigo Abonia, Jean Rodriguez, Yoann Coquerel, J. Org. Chem. 2015, 80, 9767.

The Aryne aza-Diels?Alder Reaction: Flexible Syntheses of Isoquinolines

Juan-Carlos Castillo, Jairo Quiroga, Rodrigo Abonia, Jean Rodriguez, Yoann Coquerel, Org. Lett. 2015, 17, 3374-3377.

Enamine Activation of beta-Ketocarbonyls: New Opportunities in Enantioselective Organocatalysis

Jean Rodriguez and Yoann Coquerel ChemCatChem 2015, 7, 1263-1264.

Enantioselective Synthesis of Medium-Sized-Ring Lactones by Organocatalytic Michael Addition Followed by Reductively Initiated Fragmentation

Mylène Roudier, Thierry Constantieux, Adrien Quintard, Jean Rodriguez, 2015, Eur. J. Org. Chem. 2015, 5709,

Exploiting the Reactivity of 1,2-Ketoamides: Enantioselective Synthesis of Functionalized Pyrrolidines and Pyrrolo-1,4-benzodiazepine-2,5-diones

Paola Acosta, Diana Becerra, Sébastien Goudedranche, Jairo Quiroga, Thierry Constantieux, Damien Bonne, Jean Rodriguez Synlett 2015, 26, 1591?1595

Synergistic Cuamine catalysis for the enantioselective synthesis of chiral cyclohexenones

Adrien Quintard and Jean Rodriguez, Chem. Commun. 2015, 51, 9523.

The Wolff Rearrangement: Tactics, Strategies and Recent Applications in Organic Synthesis

Y. Coquerel, J. Rodriguez, In Molecular Rearrangements in Organic Synthesis, Ed.: C. Rojas, John Wiley & Sons, Hoboken, NJ, 2015, Chap 3, pp. 59-84.

Origin of the Enantioselectivity in Organocatalytic Michael Additions of beta-Ketoamides to alpha,beta-Unsaturated Carbonyls: A Combined Experimental, Spectroscopic and Theoretical Study

A. Quintard, D. Cheshmedzhieva, M. M. Sanchez?Duque, A.Gaudel-Siri, J.-V. Naubron, Y. Génisson, J.-C. Plaquevent, X. Bugaut, J. Rodriguez, T. Constantieux, Chem. Eur. J. 2015, 21, 778.

A Stable N-Heterocyclic Carbene Organocatalyst for Hydrogen/Deuterium Exchange Reactions between Pseudo-acids and Deuterated Chloroform

F. Perez, Y. Ren, T. Boddaert, J. Rodriguez, Y. Coquerel, J. Org. Chem. 2015, 80, 1092-1097,.

Metal-Free Multicomponent Syntheses of Pyridines

C. Allais, J.-M. Grassot, J. Rodriguez, T. Constantieux, Chem. Rev. 2014, 114, 10829-10868.

1,3-Dicarbonyls in Multicomponent Reactions

X. Bugaut, T. Constantieux, Y. Coquerel, J. Rodriguez, In Multicomponent Reactions in Organic Synthesis, Eds.: J. Zhu, Q. Wang, M.-X. Wang, Wiley-VCH, Weinheim, 2014, Chap. 5, pp 109-158.

Divergent Chemo-­, Regio?, and Diastereoselective Normal Electron-Demand Povarov-Type Reactions with alpha-Oxo-ketene Dienophiles

J. Galvez, J.-C. Castillo, J. Quiroga, M. Rajzmann, J. Rodriguez, Y. Coquerel, Org. Lett. 2014, 16, 4126-4129.

N-Heterocyclic Carbene-Catalyzed Carba-, Sulfa- and Phospha-Michael Additions with NHC?CO2 Adducts as Precatalysts

M. Hans, L. Delaude, J. Rodriguez, Y. Coquerel, J. Org. Chem. 2014, 79, 2758-2764.

A temporary-bridge strategy for enantioselective organocatalyzed synthesis of aza-seven-membered rings

Sébastien Goudedranche, David Pierrot, Thierry Constantieux, Damien Bonne and Jean Rodriguez Chem. Commun., 2014, 50 (98), 15605 - 15608

1-Nitrocyclohexene

David Pierrot, Damien Bonne, Jean Rodriguez 2014, e-EROS Encyclopedia of Reagents for Organic Synthesis. 1?5.

Iron Cyclopentadienone Complexes: Discovery, Properties, and Catalytic Reactivity

A. Quintard, J. Rodriguez Angew. Chem. Int. Ed. 2014, 53, 4044-4055.

Preyssler Heteropoly Acids Encapsulated in a Silica Framework for an ­Efficient Preparation of Fluorinated Hexahydropyrimidine Derivatives under Solvent-Free Conditions

Ángel G. Sathicq, Diego M. Ruiz, Tierry Constantieux, Jean Rodriguez, Gustavo P. Romanelli Synlett 2014, 25(6), 881-883,

Organocatalytic Enantioselective Multicomponent Synthesis of Pyrrolopiperazines

H. Du, J. Rodriguez, X. Bugaut, T. Constantieux Adv. Synth. Catal. 2014, 356, 851-856,

alpha,beta-Unsaturated Acyl Cyanides as New Bis-Electrophiles for Enantioselective Organocatalyzed Formal [3+3] Spiroannulation

S. Goudedranche, X. Bugaut, T. Constantieux, D. Bonne, J. Rodriguez, Chem. Eur. J. 2014, 20, 410-415. (Highlighted in Synform, 2014, 4, A49)

Enantioselective Organocatalytic Multicomponent Synthesis of 2,6-Diazabicyclo[2.2.2]octanones

M. M. Sanchez Duque, O. Baslé, Y. Génisson, J.-C. Plaquevent, X. Bugaut, T. Constantieux, J. Rodriguez, Angew. Chem. Int. Ed. 2013, 52, 14143-14146. (Highlighted in Synfacts, 2014, 10, 137),

Design, Synthesis, and Organocatalytic Activity of N-Heterocyclic Carbenes Functionalized with Hydrogen-Bond Donors in Enantioselective Reactions of Homoenolates

Faisal Nawaz, Mehdi Zaghouani, Damien Bonne, Olivier Chuzel, Jean Rodriguez, and Yoann Coquerel Eur. J. Org. Chem. 2013, 8253-8264.

Temporary Intramolecular Generation of Pyridine Carbenes in Metal-Free Three-Component C_H Bond Functionalisation/Aryl-Transfer Reactions

Faisal Nawaz, Kishor Mohanan, Laurence Charles, Michel Rajzmann, Damien Bonne, Olivier Chuzel, Jean Rodriguez, and Yoann Coquerel Chem. Eur. J. 2013, 19, 17578 - 17583.

An Iron/Amine-Catalyzed Cascade Process for the Enantioselective Functionalization of Allylic Alcohols

A. Quintard, T. Constantieux, J. Rodriguez, Angew. Chem. Int. Ed. 2013, 52, 12883-12887.

Michael Addition-Initiated Sequential Reactions from 1,3-Dicarbonyls for the Synthesis of Polycyclic Heterocycles

X. Bugaut, D. Bonne, Y. Coquerel, J. Rodriguez, T. Constantieux, Curr. Org. Chem. 2013, 1920-1928.

Enantioselective Organocatalyzed Domino Synthesis of Six-Membered Carbocycles

Sébastien Goudedranche, Wilfried Raimondi, Xavier Bugaut, Thierry Constantieux, Damien Bonne and Jean Rodriguez Synthesis 2013, 1909-1930.

Metal-free Michael addition-initiated three-component reaction for the regioselective synthesis of highly functionalized pyridines: scope, mechanistic investigations and applications

Christophe Allais, Frédéric Liéby-Muller, Thierry Constantieux and Jean Rodriguez Eur. J. Org. Chem. 2013, 2013, 19, 4131-4145.

Tartrate-based ionic liquids: unified synthesis and characterisation

Anne Rouch, Tessa Castellan, Isabelle Fabing, Nathalie Saffon, Jean Rodriguez, Thierry Constantieux, Jean-Christophe Plaquevent and Yves Génisson RSC Adv., 2013, 3, 413-426

Michael Additions in Aqueous Media: 'On-Water' and 'In-Water' Processes from a-Nitroketones and their Anions

G. Giorgi, P. López-Alvarado, S. Miranda, J. Rodriguez, J. C. Menéndez Eur. J. Org. Chem. 2013, 1327.

Cascade Reactions Forming both C-C Bond and C-Heteroatom Bond

D. Bonne, T. Constantieux, Y. Coquerel, J. Rodriguez, dans 'Stereoselective Organocatalysis: Bond Formation Methodologies and Activation Modes', R. Rios Torres, Ed., John Wiley & Sons, Hoboken, New Jersey, 2013, Chap. 16, p. 559-585.

Reactions Involving an alpha,beta-Unsaturated Compound as Electrophilic Component with the Michael Addition as the Key Step

J. Rodriguez, D. Bonne, Y. Coquerel, T. Constantieux, dans 'Multicomponent Reactions 2', 'Science of Synthesis Reference Library', T. J. J. Müller, Ed., Thieme, Stuttgart, 2013, Chap. 2.1.1, p. 1-36.

Microwave-Assisted Stereoselective Synthesis

Y. Coquerel, E. Colacino, J. Rodriguez, J. Martinez, F. Lamaty, in Stereoselective Synthesis of Drugs and Natural Products, Eds: V. Andrushko, N. Andrushko, Wiley- Blackwell, Hoboken, NJ, 2013, Chap. 5, in press. 

Activation of 1,2- and 1,3-Ketoamides with Thiourea Organocatalyst for the Enantioselective Domino Synthesis of Fuctionalized Cyclohexanes

W. Raimondi, M. M. Sanchez Duque, S. Goudedranche, A. Quintard, T. Constantieux, X. Bugaut, D. Bonne, J. Rodriguez Synthesis, 2013, 45, 1659-1666.

Practical and Efficient Organocatalytic Enantioselective ?- Hydroxyamination Reactions of ?-Ketoamides

D. Mailhol, J.-C. Castillo, K. Mohanan, R. Abonia, Y. Coquerel, J. Rodriguez, ChemCatChem 2013, 5, 1192-1199

Stereoselective Multiple Bond-Forming Transformations (MBFTs): The Power of 1,2- and 1,3-Dicarbonyl Compounds

D. Bonne, T. Constantieux, Y. Coquerel, J. Rodriguez, Chem.-Eur. J. 2013, 19, 2218-2231. 

Syntheses and Applications of Functionalized Bicyclo[3.2.1]octanes: Thirteen Years of Progress

M. Presset, Y. Coquerel, J. Rodriguez, Chem. Rev. 2013, 113, 525-595. 

Expeditious, Metal-Free, Domino, Regioselective Synthesis of Highly Substituted 2-Carbonyl- and 2-Phosphorylfurans by Formal [3+2] Cycloaddition

Wilfried Raimondi, Daniel Dauzonne, Thierry Constantieux, Damien Bonne, Jean Rodriguez Eur. J. Org. Chem. 2012, 6119-6123.

Expeditious Synthesis of the Cores of Naturally Occurring Cyclic Polyethers using a Divergent Ring Rearrangement Metathesis Strategy

P. Escavabaja, J. Viala, Y. Coquerel, J. Rodriguez, Adv. Synth. Catal., 2012, 354, 3200-3204.

Enantioselective Organocatalytic Michael Addition of Cyclobutanones to Nitroalkenes

D. Mailhol, M. M. Sanchez Duque, W. Raimondi, D. Bonne, T. Constantieux, Y. Coquerel, J. Rodriguez, Adv. Synth. Catal.,2012, 354, 3523-3532.

Dual Heterogeneous Catalysis for a Regioselective Three- Component Synthesis of Bi- and Tri(hetero)arylpyridines

Christophe Allais, Frédéric Liéby-Muller, Thierry Constantieux, Jean Rodriguez Adv. Synth. Catal. 2012, 354 (13), 2537-2544.

Cooperative Heterogeneous Organocatalysis and Homogeneous Metal Catalysis for the One-Pot Regioselective Synthesis of 2-Pyridones

Christophe Allais, Olivier Baslé, Jean-Marie Grassot, Maxime Fontaine, Stéphane Anguille, Jean Rodriguez, Thierry Constantieux Adv. Synth. Catal. 2012, 354 (11-12), 2084-2088.

Transition-Metal-Free alpha-Arylation of beta-Keto Amides via an Interrupted Insertion Reaction of Arynes

Kishor Mohanan, Yoann Coquerel, Jean Rodriguez, Org. Lett. 2012, 14, 4686-4689.

Catalyst- and Halogen-Free Regioselective Friedel-Crafts ?-Ketoacylations

Kishor Mohanan, Marc Presset, Damien Mailhol, Yoann Coquerel, Jean Rodriguez Chem. Eur. J. 2012, 18: 9217-9220

Asymmetric transformations involving 1,2-diarbonyl compounds as pronucleophiles

W. Raimondi, D. Bonne, J. Rodriguez, Chem. Commun. 2012, 48, 6763

Microwave-Assisted Domino Benzannulation of ?-Oxo Ketenes: Preparation of 1,3-Dihydro-2H-1,5-benzodiazepin-2-ones

Juan-Carlos Castillo, Marc Presset, Rodrigo Abonia, Yoann Coquerel, Jean Rodriguez Eur. J. Org. Chem. 2012, 2338-2345

Asymmetric organocascades involving the formation of two C-heteroatom bonds from two distinct heteroatoms

Damien Bonne , Thierry Constantieux , Yoann Coquerel andJean Rodriguez, Org. Biomol. Chem., 2012,10, 3969-3973

Activation of 1,2-Ketoesters with Takemoto's Catalyst toward Michael Addition to Nitroalkenes

Wilfried Raimondi, Olivier Baslé, Thierry Constantieux, Damien Bonne, Jean Rodriguez, Adv. Synth. Catal. 2012, 354, 563-568.

1,2-Dicarbonyl Compounds as Pronucleophiles in Organocatalytic Asymmetric Transformations

Wilfried Raimondi, Damien Bonne, and Jean Rodriguez Angew. Chem. Int. Ed. 2012, 51, 40-42

Single-Step Metallocatalyzed and Organocatalyzed Enantioselective Construction of Bicyclo[3.2.1]octanes

M. PRESSET, Y. COQUEREL, J. Rodriguez, ChemCatChem (Highlight) 2012, 4, 172-174.

Stereoselective Multicomponent Reactions: from Simple 1,3-Dicarbonyls to Functionalized Chiral Heterocycles

D. Bonne, Y. Coquerel, T. Constantieux, J. Rodriguez in Targets in Heterocyclic Systems - Chemistry and Properties, Vol. 15, Eds.: O. A. Attanasi, D. Spinelli, Societa? Chimica Italiana, Roma, 2011, pp. 140-163. 

Multicomponent reactions in ionic liquids: convenient and ecocompatible access to the 2,6-DABCO core

Z. El Asri, Y. Génisson, F. Guillen, O. Baslé, N. Isambert, M. M. Sanchez Duque, S. Ladeira, J. Rodriguez, T. Constantieux, J-C. Plaquevent Green Chem., 2011, 13, 2549-2552.

Selected for SYNFACTS by Benjamin List and Manuel Mahlau: Asymmetric Michael Addition of alpha-Substituted beta-Keto Amides

Maria del Mar Sanchez Duque, Olivier Baslé, Nicolas Isambert, Anouk Gaudel-Siri, Yves Génisson, Jean-Christophe Plaquevent, Jean Rodriguez and Thierry Constantieux Synfacts 2011, 8, 0904

1,3-Dipolar Cycloaddition of Hydrazones with ?-Oxo-ketenes: A Three-Component Stereoselective Entry to Pyrazolidinones and an Original Class of Spirooxindoles

Marc Presset, Kishor Mohanan, Marie Hamann, Yoann Coquerel, and Jean Rodriguez Org. Lett. 2011, 13, 4124-4127

Diazo Transfer Reactions to 1,3-Dicarbonyl Compounds with Tosyl azide

Marc Presset, Damien Mailhol, Yoann Coquerel, Jean Rodriguez Synthesis 2011, 2549-2552

A Cooperative Participation of the Amido Group in the Organocatalytic Construction of All-Carbon Quaternary Stereocenters by Michael Addition with beta-Ketoamides

Maria del Mar Sanchez Duque, Olivier Baslé, Nicolas Isambert, Anouk Gaudel-Siri, Yves Génisson, Jean-Christophe Plaquevent, Jean Rodriguez and Thierry Constantieux Org. Lett. 2011, 13, 3296-3299

Consecutive Reactions with Sulfoximines: Straightforward Synthesis of Substituted 5,5-Spiroketals

Vellaisamy Sridharan, Nikolay Vologdin, Marie-Alice Virolleaud, Cyril Bressy, Gaëlle Chouraqui, Laurent Commeiras, Jean-Luc Parrain, Damien Bonne,Yoann Coquerel, Jean Rodriguez Synthesis 2011, 2085-2090.

A General, Diastereoselective Synthesis of Highly Functionalized Bicyclo[n.3.1]alkane Systems Based on an Anionic Domino Reaction of alpha-Nitrocycloalkanones

Giorgio Giorgi, Sonia Miranda, Miriam Ruiz, Jean Rodriguez, Pilar López-Alvarado, and J. Carlos Menéndez Eur. J. Org. Chem. 2011, 2101-2110.

Multicomponent reactions and ionic liquids: a perfect synergy for eco-compatible heterocyclic synthesis

N. Isambert, M. M. Sanchez Duque, J.-C. PLaquevent, Y. Génisson, J. Rodriguez, T. Constantieux, Chem. Soc. Rev., 2011, 40, 1347-1357.

N-Heterocyclic Carbene-Catalyzed Michael Additions of 1,3-Dicarbonyl Compounds

T. Boddaert, Y. Coquerel, J. Rodriguez, Chem. Eur. J. 2011, 17, 2266-2271.

Expeditious Divergent Synthetic Approach to Polycyclic Terpene-like Molecules

T. Boddaert, Y. Coquerel, J. Rodriguez, Chem. Eur. J. 2011, 17, 2048-2051.

Expeditious Synthesis and Biological Evaluation of New C-6 1,2,3-Triazole Adenosine Derivatives A1 Receptor Antagonists or Agonists

Smitha C. Mathew, Youlet By, Aurélie Berthault, Marie-Alice Virolleaud, Louis Carrega, Gaëlle Chouraqui, Laurent Commeiras, Jocelyne Condo, Mireille Attolini, Anouk Gaudel-Siri, Jean Ruf, Jean Rodriguez, Jean-Luc Parrain and Régis Guieu Org. Biomol. Chem. 2010, 8, 3874-3881

Highly diastereo- and enantioselective organocatalytic Micheal addition of a-ketoamides to nitroalkenes

O. Baslé, W. Raimondi, M. M. Sanchez Duque, D. Bonne, T. Constantieux, J. Rodriguez. Org. Lett., 2010, 12, 5246-5249.

One-pot asymmetric cyclocarbohydroxylation sequence for the enantioselective synthesis of functionalised cyclopentanes

Wilfried Raimondi, Grégory Lettieri, Jean-Pierre Dulcère, Damien Bonne and Jean Rodriguez Chem, Commun, 2010, 46, 7247-7249.

Utilisation des dérivés 1,3-dicarbonylés dans les réactions domino et multicomposé

Damien Bonne, Thierry Constantieux, Yoann Coquerel, Jean Rodriguez Techniques de l'Ingénieur 2010, CHV2210

1,3-Dicarbonyl compounds in stereoselective domino and multicomponent reactions

Damien Bonne, Yoann Coquerel, Thierry Constantieux, Jean Rodriguez Tetrahedron: Asymmetry 2010, 21, 1085-1109

beta-diketo building blocks for MCRs-based syntheses of heterocycles

M.M. Sanchez Duque, C. Allais, N. Isambert, T. Constantieux, J. Rodriguez Top. Heterocyclic. Chem. 2010, 23, 227-277

Quadrane Sesquiterpenes: Natural Sources, Biology, and Syntheses

Marc Presset, Yoann Coquerel, Jean Rodriguez Eur. J. Org. Chem. (microreview) 2010, 2247-2260.

Multiple Bond-Forming Transformations: the Key Concept towards Eco-compatible Synthetic Organic Chemistry

Yoann Coquerel, Thomas Boddaert, Marc Presset, Damien Mailhol, Jean Rodriguez in Ideas in Chemistry and Molecular Sciences, Vol.1 Advances in synthetic chemistry, Chap 9, pp 187-202, Pignataro B. Ed., Wiley-VCH, Weinheim, 2010.

Design, synthesis and biological evaluation of bivalent m opiate and adenosine A1 receptor antagonist.

S. C. Mathew, N. Ghosh, Y. By, A. Berthault, M. A. Virolleaud, L. Carrega, G. Chouraqui, L. Commeiras, J. Condo, M. Attolini, A. gaudel-SIRI, J. Ruf, J. L. Parrain, J. Rodriguez, R. Guieu, Bioorg. Med. Chem. Lett. 2009, 19, 6736-6739.

Michael Addition Initiated Carbocyclization Sequences with Nitroolefins for the Stereoselective Synthesis of Functionalized Heterocyclic and Carbocyclic Systems

Estelle Dumez, Anne-Catherine Durand, Martial Guillaume, Pierre-Yves Roger, Robert Faure, Jean-Marc Pons, Gaetan Herbette, Jean-Pierre Dulcere, Damien Bonne, and Jean Rodriguez Chem. Eur. J. 2009, 15, 12470-2488

Consecutive reactions with sulfoximines: A direct access to 2-sulfonimidoylylidene tetrahydrofurans and 6-sulfonimidoylmethyl-3,4-dihydro-2H-pyrans

M.-A. Virolleaud, V. Sridharan, D. Mailhol, D. Bonne, C. Bressy, G. Chouraqui, L. Commeiras, Y. Coquerel, J. Rodriguez Tetrahedron, 2009, 65, 9756-9764.

Highly efficient synthesis of trans-beta,gama-unsaturated-alpha-keto amides

Christophe Allais, Thierry Constantieux, and Jean Rodriguez synthesis 2009, 2523-2530,

User friendly stereoselective one-pot access to 1,4-diazepane derivatives by a cyclodehydrative three-component reaction with 1,3-dicarbonyls

Enrique Sotoca, Christophe Allais, Thierry Constantieux, Jean Rodriguez Org. Biomol. Chem., 2009, 7, 1911-1920

Microwave-assisted Cross-metathesis of Acrylonitrile

Thomas Boddaert, Yoann Coquerel, Jean Rodriguez C. R. Chimie 2009, 12, 872-875.

Palladium-Catalysed Isomerisation of 2-Vinylidenehydrofurans into 1,3-Dienes and some Aspects of their Reactivity

Abdelkader Ghobsi, Salih Hacini, Laurence Wavrin, Anouk Gaudel-Siri, Agnès Corbères, Cyril Nicolas, Damien Bonne, Jacques Viala, and Jean Rodriguez Eur. J. Org. Chem. 2008, 4446-4453

Microwave-Assisted Olefin Metathesis

Yoann Coquerel, Jean Rodriguez Eur. J. Org. Chem. (microreview) 2008, 1125-1132

Synthetic Studies Towards Guaianolide Sesquiterpene Lactones

Isabelle Reboul, Thomas Boddaert, Yoann Coquerel, Jean Rodriguez Eur. J. Org. Chem. 2008, 5379-5382

Stereoselective Synthesis of Bicyclo[4.2.1]nonanes: a Temporary-Bridge Approach to Cyclooctanoids

Antoine Michaut, Sonia Miranda-García, J. Carlos Menéndez,Yoann Coquerel, Jean Rodriguez Eur. J. Org. Chem. 2008, 4988-4998.

Metal-free Michael addition initiated multicomponent oxidative cyclodehydration route to polysubstituted pyridines from 1,3-dicarbonyls

Frédéric Liéby-Muller, Christophe Allais, Thierry Constantieux and Jean Rodriguez, Chem. Commun., 2008, 4207-4209

Catalytic Properties of the Pd/C - Triethylamine System

Yoann Coquerel, Jean Rodriguez Arkivoc 2008 (xi) 227-237.

Bicyclic 5-6 Systems with One Bridgehead (Ring Junction) Nitrogen Atom: Two Extra Heteroatoms 0:2

J. Rodriguez, T. Constantieux. Comprehensive Heterocyclic Chemistry III, AR Katritzky, CA Ramsden, EFV Scriven and RJK Taylor, Eds., Elsevier: Oxford, 2008, Vol. 11, pp 629 - 644.

Reluctant Cross-Metathesis Reactions: a Highly Beneficial Effect of Microwave Irradiation

Michaut, A,, Boddaert, T., Coquerel, Y., Rodriguez, J. Synthesis 2007, 2867-2871

Pd-H from Pd/C and Triethylamine: Implications in Palladium Catalysed Reactions Involving Amines

Coquerel, Y., Brémond, P., Rodriguez, J. J. Organomet. Chem. 2007, 692, 4805-4808.

Stereoselective Synthesis of the Core of Naturally Occurring Anti-HIV Isolitseane B

Brémond, P., Girardeau, E., Coquerel, Y., Rodriguez Lett. Org. Chem. 2007, 4, 232-233