Institut des Sciences Moléculaires de Marseille Université Paul cézanne Aix Marseille III
               
       

 

Dr. Marius REGLIER

AMU iSm2 Service 342
Campus Scientifique de St Jérôme
13397 Marseille cedex 20

 

Phone : 0491 28 88 23

Fax : 0491 28 84 40

E-Mail : marius.reglier{noSPAM}univ-amu.fr

Other web site: www.biosciences.univ-cezanne.fr

 

Career

Education:
1975:
Master in Sciences, Paul Cézanne Univ. Aix-Marseille III.
1976: Chemical Ingeneer, Ecole Supérieure de Chimie de Marseille.
1980: First Ph. D., Paul Cézanne Univ. Aix-Marseille III, September 26, 1980: Reactivity of non-conjugated dienes towards the catalytic system PdCl2/CuCl2: cyclisation and allylic oxidations (Pr. B. Waegell and Dr. A. Heumann).
1984: Second Ph. D. (thèse d’Etat), Pierre and Marie Curie Univ. Paris VI, December 18, 1984: Syntheses and Reactivity of Thia and 1-Aza-3-Cyclohexenes (Dr. S. Julia).

Experience:
1980-1984: CNRS Researcher (CR2), Ecole Normale Supérieure, Pierre and Marie Curie Univ. Paris VI, Dr. S. Julia
1985-1986: Research Fellow; University of Geneva, Switzerland, Pr. W. Oppolzer.
1986-1994: CNRS Researcher (CR1), Paul Cézanne Univ. Aix-Marseille III, Pr. B. Waegell
1989-1990: Research Fellow, Lab. of Cellular and Molecular Neurobiology, Gif/Yvette, Dr. J. Mallet.
1992: Visiting scientist, Johns Hopkins Univ., Baltimore, USA, Pr. K. D. Karlin.
1994- : CNRS Researcher (DR2 then DR1), Paul Cézanne Univ. Aix-Marseille III.

Awards:
2002: “Docteur et de Madame Henri Labbé” prize from the French Academy of Science.
2002: JSPS fellowship
2011: CNRS Excellence in Science

Teaching experience

- “Electron Paramagnetic Resonance Spectroscopy”, Bachelor courses in Chemistry, Univ. of La Réunion.
- “Chemistry of living organisms”, Bachelor courses in Physical and Chemical Sciences, Paul Cézanne Univ. Aix-Marseille III.
- “Chemical tools for the study of biomolecules”, Master courses in Chemistry, Paul Cézanne Univ. Aix-Marseille III.
- “Metals and Nutrition”, Master courses in Nutrition and Food Safety, Paul Cézanne Univ. Aix-Marseille III.
- “Introduction to Inorganic Chemistry in Biology”, Ph. D. courses, Naples Federico II Univ., Italy.
- “Copper-containing monooxygenases and related enzymes”, Summer School in from chemistry to biology and médicine via metals, Heraklion Univ., Greece.

Research interests:

- Cu-containing monooxygenases: Tyrosinase (Ty), Dopamine -Hydroxylase (DH), Peptidylglycine -Amidating Monooxygenase (PAM), particulate Methane MonoOxygenase (pMMO).
- Biomimetic chemistry focused on functional and structural metalloenzyme models,
- Study of mechanism-based inhibitors of DH, PAM and Ty,
- Purification and genetic expression of copper-containing monooxygenases.

Management responsibilities

1996-2004: member of the organising committee of REncontres de Chimie Organique Biologique (President for RECOB8, 2000)
2000-2004: appointed member of the CNRS Comité National section 20
2001-2006: President of the GIS CNRS/Univ. Paul Cézanne « Club CNRS Métalloprotéines et Modèles

2006-2011: Member of the scientific committee of the Indo-French Center for the Promotion of the Advanced Research (CEFIPRA/IFCPAR)
2006-2008: Head of the FRE CNRS 3005 BiosCiences

2007-2009: member of the scientific committee of the ANR program “blanc”
2009-2012: Vice-president of the ANR program “Retour Post-doctorant”
2012-: Scientific officier at the Institut de Chimie du CNRS

Selected Publications

Titre
Auteurs
R. Haudecoeur, M. Carotti, A. Gouron, M. Maresca, E. Buitrago, R. Hardré, E. Bergantino, H. Jamet, C. Belle, M. Réglier, L. Bubacco and A. Boumendjel. ACS Med. Chem. Lett. 2017, 8 (1), 55-60. 
A. L. Concia, M. R. Beccia, M. Orio, F. Terra Ferre, M. Scarpellini, F. Biaso, B. Guigliarelli, M. Réglier, A. J. Simaan Inorg. Chem., 2017, 56, 1023?1026. 
E. Buitrago, R. Hardré, R. Haudecoeur, H. Jamet, C. Belle, A. Boumendjel, L. Bubacco and M. Réglier. Current Topics in Medicinal Chemistry 2016, 16(27), 3033-3047. 
J. A. Isaac, F. Gennarini, I. López, A. Thibon-Pourret, R. David, G. Gellon, B. Gennaro, C. Philouze, F. Meyer, S. Demeshko, Y. Le Mest, M. Réglier, H. Jamet, N. Le Poul and C. Belle. Inorg. Chem. 2016, 55, 8263-8266. 
M.-C. Kafentzi, M. Orio, M. Réglier, S. Yao, U. Kuhlmann, P. Hildebrandt, M. Driess, A. J. Simaan and K. Ray. Dalton trans. 2016, 45, 15994-16000. 
D. Lakk-Bogáth, R. Csonka, G. Speier, M. Réglier, A. J. Simaan, J.-V. Naubron, M. Giorgi, K. Lázár, J. Kaizer. Inorg. Chem. 2016, 55, 10090-10093. 
T. Straistari, J. Fize, S. Shova, M. Réglier, V. Artero and M. Orio. ChemCatChem 2016, DOI: 10.1002/cctc.201600967 
O. Cuzan, A. Kochem, A. J. Simaan, S. Bertaina, B. Faure, V. Robert, S. Shova, M. Giorgi, M. Maffeď, M. Réglier and M. Orio. Eur. J. Inorg. Chem. 2016, 5575-5584. 
Yasmina Mekmouche, Ludovic Schneider, Pierre Rousselot-Pailley, Bruno Faure, A. Jalila Simaan, Constance Bochot, Marius Réglier, Thierry Tron Chem. Sci., 2015, 6, 1247-1251 
"Marius Réglier, A. Jalila Simaan in RSC Metallobiology Series No. 3 ""2-Oxoglutarate-Dependent Oxygenases"", Edited by Robert P. Hausinger and Christopher J. Schofield, The Royal Society of Chemistry 2015" 
Schicke, Olivier, Faure, Bruno, Carissan, Yannick, Giorgi, Michel, Simaan, Ariane Jalila, Reglier, Marius EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2015, Issue: 21 Pages: 3512-3518 
Madleen Sallmann, Fabio Oldenburg, Beatrice Braun, Marius Réglier, A. Jalila Simaan, Christian Limberg Angew. Chem. Int. Ed., 2015, 54 (42), 12325?12328 
Ludovic Schneider, Yasmina Mekmouche, Pierre Rousselot-Pailley, A. Jalila Simaan, Viviane Robert, Marius Réglier, Ally Aukauloo, and Thierry Tron ChemSusChem, 2015, 8 (18), 3048?3051 
C. Justino Nunes, B. Essenfelder Borges, L. Sumie Nakao, E. Peyroux, R. Hardré, B. Faure, M. Réglier, M. Giorgi, M. Pietro Bach, C. Columbano de Oliveira and A. M. Da Costa Ferreira. J. Inorg. Biochem. 2015, 149, 49-58. 
C. Bochot, A. Gouron, L. Bubacco, A. Milet, C. Philouze, M. Réglier, G. Serratrice, H. Jamet and C. Belle. Chem. Commun. 2014, 50, 308-3010. 
O. Cuzan, T. Straistari, C. Turta and M. Réglier. Acta Cryst. Section E, Structure reports online 2014, 70(Pt 1), o4. 
R. Haudecoeur, A. Gouron, C. Dubois, H. Jamet, M. Lightbody, R. Hardré, Anne Milet, E. Bergantino, L. Bubacco, C. Belle, M. Réglier and A. Boumendjel. ChemBioChem 2014, 15(9), 1325?1333. 
E. Buitrago, A. Vuillamy, A. Boumendjel, W. Yi, G. Gellon, R. Hardre, Renaud, G. Serratrice, M. Réglier, C. Belle. Inorg. Chem. 2014, 53, 12848-12858. 
Theodore Lazarides, Igor Sazanovich, A. Jalila Simaan, Maria Chrisanthi Kafentzi, Milan Delor, Yasmina Mekmouche, Bruno Faure, Marius Reglier, Julia Weinstein, Athanassios Coutsolelos, Thierry Tron J. Am. Chem. Soc. 2013, 135, 3095?3103 
Papadakis, Raffaello, Riviere, Eric, Giorgi, Michel, Rousselot-Pailley, Pierre, Reglier, Marius, Simaan, A. Jalila, Tron, Thierry Inorg. Chem. 2013, 52, 5824?5830 
C. Bochot, E. Favre, C. Dubois, B. Baptiste, P.-A. Carrupt, G. Gellon, R. Hardré, D. Luneau, A. Nurisso, M. Reglier, G. Serratrice, C. Belle and H. Jamet. Chem. Eur. J. 2013, 19, 3655-3664. 
Olivier Schicke, Bruno Faure, Michel Giorgi, A. Jalila Simaan, Marius Reglier, Inorg. Chim. Acta 2012, 391, 189-194 
Lydie Brisson Nadia El Bakkali-Taheri, Michel Giorgi, Antoine Fadel, József Kaizer, Marius Reglier, Thierry Tron, El Hassan Ajandouz, A. Jalila Simaan , J. Biol. Inorg. Chem., 2012 , 17, 939-949 
C. Dubois, R. Haudecoeur, M. Orio, C. Belle, C. Bochot, A. Boumendjel, R. Hardré, H. Jamet and M. Reglier. ChemBioChem 2012, 13, 559-565. 
O. Schicke, B. Faure, M. Giorgi, A. J. Simaan and M. Reglier. Inorg. Chim. Acta 2012, 391 (2012) 189-194. 
A. Jalila Simaan, Yasmina Mekmouche, Pierre Moreno, Ally Aukauloo, Jacques Delaire, Marius Reglier, Thierry Tron Chem. Eur. J. 2011, 17, 11743 - 11746 
T. Lazarides, G. Charalambidis, A. Vuillamy, M. Reglier, E. Klontzas, G. Froudakis, S. Kuhri, D. M. Guldi and A. G. Coutsolelos Inorg. Chem. 2011, 50, 8926-8936. 
Langella E., Pierre S., Ghattas W., Giorgi M., Reglier M., Saviano M., Esposito L. and Hardré R. ChemMedChem, 2010, 5(9), 1568-76. 
Orio, M., Bochot, C., Dubois, C., Gellon, G. , Hardré, R., Jamet, H., Luneau, D., Philouze, C., Reglier, M., Serratrice, G. Chemistry--A European Journal, 2011, 17(48), 13482-13494 
By Yi W., Dubois C., Yahiaoui S., Haudecoeur R., Belle C., Song H., Hardré R., Reglier M., Boumendjel A. Eur. J. Med. Chem. , 2011, 46(9), 4330-5 
Wadih Ghattas, Zeinab Serhan, Nadia El Bakkali-Taheri, Marius Reglier, Masahito Kodera, Yutaka Hitomi, A. Jalila Simaan Inorg. Chem.. 2009, 48, 3910-3912 
E. Peyroux, W. Ghattas, R. Hardré, M. Giorgi, B. Faure, A. J. Simaan, C. Belle, M.Reglier.(2009) Inorg. Chem. 48, 10874-10876. 
A. Kupan, J. Kaizer, G. Speier, M. Giorgi, M. Reglier, F. Pollreisz.(2009) J. Inorg. Biochem. 103, 389-395. 
P. Slama, J.-L. Boucher, M. Reglier.(2009) J. Inorg. Biochem. 103, 455-462. 
Csonka R., Kaizer J., Giorgi M., Reglier M., Hajba, L., Mink J., Speier G. (2008) Inorganic Chemistry 47(14), 6121-6123. 
Slama P., Boucher J.-L., Reglier M. (2008) Journal of Inorganic Biochemistry, sous presse. 
Ghattas W., Giorgi M., Mekmouche Y., Tanaka T., Rockenbauer A., Reglier M., Hitomi Y., Simaan A. J. (2008) Inorganic Chemistry 47(11), 4627-4638. 
Kaizer J., Ganszky I., Speier G., Rockenbauer A., Korecz L., Giorgi M., Reglier M., Antonczak S. (2007) Journal of Inorganic Biochemistry 101(6), 893-899. 
Kaizer J., Barath G., Pap J., Speier G., Giorgi M., Reglier M. (2007) Chemical Communications 48, 5235-5237. 
J. Kaizer, Z. Zsigmond, I. Ganszky, G. Speier, M. Giorgi, M. Reglier(2007) Inorg. Chem. 46, 4660-4666. 
Kaizer, Jozsef, Barath, Gabor, Speier, Gabor, Reglier, Marius, Giorgi, Michel. Inorganic Chemistry Communications (2007), 10(3), 292-294. 
Slama, Patrick, Reglier, Marius. Comptes Rendus Chimie (2007), 10(8), 731-741. 
W. Ghattas, M. Giorgi, C. Gaudin, A. Rockenbauer, M. Reglier and A. J. Simaan. Bioinorganic Chemistry and Applications 2007, Article ID 43424, 9 pages. 
P. Slama, M. Reglier(2007) C. R. Chimie 10, 731-741. 
W. Ghattas, C. Gaudin, M. Giorgi, A. Rockenbauer, A. J. Simaan, M. Reglier Chem. Commun. 2006, 1027-1029. 
J. Kaizer, T. Csay, G. Speier, M. Reglier and M. Giorgi. Inorg. Chem. Comm. 2006, 9, 1037-1039. 
K. Selmeczi, M. Giorgi, G. Speier, M. Reglier. Eur. J. Inorg. Chem. 2006, 1022-1031. 
Kaizer, S. Góger, G. Speier, M. Reglier, M. Giorgi Inorg. Chem. Comm. 2006, 9, 251-254. 
B. Tapodi, G. Speier, M. Giorgi, M. Reglier, T. Funabiki, L. Korecz, A. Rockenbauer. Inorg. Chem. Comm. 2006, 9, 367-370. 
J. Kaizer, S. Góger, G. Speier, M. Giorgi, M. Reglier. Z. Kristallogr. NCS, 2006, 221, 75-76. 
Ghattas W, Hess CR, Iacazio G, Hardré R, Klinman JP, Reglier M., J Org Chem. 2006, 71(22), 8618-21 
A. Klonowska, C. Gaudin, M. Asso, A. Fournel, M. Reglier, T. Tron Enzyme and Microbial Technology, 2005, 36, 34-41. 
É. Balogh-Hergovich, G. Speier, M. Reglier, M. Giorgi, E. Kuzmann, A. Vértes Inorg. Chem. Comm. 2005, 8, 457-459. 
J. Kaizer, R. Csonka, G. Speier, M. Giorgi, M. Reglier J. Mol. Catal. A-Chem. 2005, 235, 81-87. 
J. Kaizer, R. Csonka, G. Speier, M. Giorgi, M. Reglier J. Mol. Catal. A-Chem. 2005, 236, 12-17. 
J. Kaizer, T. Csay, M. Czaun, G. Speier, M. Reglier, M. Giorgi Inorg. Chem. Comm. 2005, 8, 813-816. 
M. Kodera, M. Itoh, K. Kano, T. Funabiki, M. Reglier Angew. Chem. Int. Ed. Engl. 2005, 44, 7104-7106. 
G. Iacazio, M. Reglier Tetrahedron: asymmetry 2005, 16, 3633-3639. 
K. Selmeczi, M. Reglier, G. Speier, G. Peintler Reaction Kinetics and Catalysis Letters 2004, 81(1), 143-151. 
P. Slama, J.-L. Boucher, M. Reglier Biochemical and Biophysical Chemical Research 2004, 316(4), 1081-1087. 
E. Balogh-Hergovich, G. Speier, M. Reglier, M. Giorgi, E. Kuzmann, A. Vertes. Inorganica Chimica Acta, 2004, 357(12), 3689-3696. 
K. Selmeczi, G. Speier, M. Reglier, M. Giorgi. Zeitschrift fuer Kristallographie - New Crystal Structures 2004, 219(2), 143-144. 
J. Kaizer, G. Speier, E. Ösz, M. Giorgi, M. Reglier Tetrahedron Lett. 2004, 45, 8011-8013. 
J. Kaizer, J. Pap, G. Speier, M. Reglier, M. Giorgi Transition Metal Chemistry, 2004, 29, 630-633. 
G. Speier, M. Reglier, M. Giorgi, E. Kuzmann, A. Vertes. Eur. J. Inorg. Chem. 2003, 1735-1740. 
K. Selmeczi, M. Reglier, M. Giorgi, G. Speier, G. Peintler.Coord. Chem. Rev. 2003, 245(1-2), 191-201. 
Blain, Ingrid, Giorgi, Michel, De Riggi, Innocenzo, Reglier, Marius. European Journal of Inorganic Chemistry (2001), (1), 205-211. 
Blain, Ingrid, Giorgi, Michel, De Riggi, Innocenzo, Reglier, Marius. European Journal of Inorganic Chemistry (2000), (2), 393-398 

 

   
   

Page modifiée le Vendredi 27 Septembre, 2013