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Dr.
 
Alain
 
ARCHELAS

Dr. Alain Archelas's picture
Dr.
Alain
ARCHELAS
AMU iSm2 Service 432
Campus Scientifique de St Jérôme
Marseille cedex 20


Téléphone
Fax
0491 28 84 40

Enseignements

Cours de Biocatalyse à l'ESIL (Luminy)

Thématiques

Biocatalyse. Etude et exploitation des Epoxyde Hydrolases
en synthèse asymétrique

Responsabilités administratives

début

Publications (17)
RéférenceRésumé graphique
Enantioselective Bio-Hydrolysis of Various Racemic and meso Aromatic Epoxides Using the Recombinant Epoxide Hydrolase Kau2

Wei Zhao, Michael Kotik, Gilles Iacazio, Alain Archelas, Advanced Synthesis and Catalysis, 2015, 357, 1895-1908. <hal-01477039>
Directed evolution of metagenome-derived epoxide hydrolase for improved enantioselectivity and enantioconvergence

Michael Kotik, Wei Zhao, Gilles Iacazio, Alain Archelas. . J. Mol. Catal.: B Enzym., 91, 44-51 (2013).
Silica-Catalysed and Highly Stereoselective Convergent and Nonconvergent Rearrangements of Menthone Enol Acetate Epoxides: Easy Access to the Four α-Hydroxymenthone Stereoisomers

Sylvain Tranchimand, Bruno Faure, Jean-Valère Naubron, Véronique Alphand, Alain Archelas, Gilles Iacazio, European Journal of Organic Chemistry, 2012. <hal-01398482>
Gibbs Free Energy of Formation of Chlordecone and Potential Degradation Products: Implications for Remediation Strategies and Environmental Fate

Jan Dolfing, Igor Novak, Alain Archelas, Hervé Macarié, Environnemental Science&Technology, 46, 8131-8139 (2012).
Epoxide hydrolases and their application in organic synthesis.

Michael Kotik, Alain Archelas, Roland Wohlgemuth. Current Organic Chemistry, 16, 451-482 (2012).
Laboratory evolution of an epoxide hydrolase - Towards an enantioconvergent biocatalyst

Alain Archelas, Veronika Famerova, Pavla Oubrechtova, Vladimir Kren. J. Biotechnol., 156, 1-10 (2011).
Free and immobilized Aspergillus niger epoxide hydrolase-catalyzed the hydrolytic kinetic resolution of racemic-p-chlorostyrene oxide in a neat organic solvent medium

Salwa Karboune, Alain Archelas, Jacques C. Baratti, Process Biochem. 45, 210-216 (2010).
Access to enantiopure aromatic epoxides and diols using epoxide hydrolases derived from total biofilter DNA.

Michael Kotik, Václav Št?pánek, Michal Grulich, Pavel Kyslík, Alain Archelas. J. Mol. Catal.: B Enzym., 65, 41-48 (2010).
Environmental DNA as a source of a novel epoxide hydrolase reacting with aliphatic terminal epoxides.

M. Kotik, V. Stepánek, H. Maresová, P. Kyslík, A. Archelas.(2009) J. Mol. Catal.: B Enz. 56, 288-293.
Epoxide hydrolase catalyzed kinetic resolution of a spiroepoxide, a key building block of various 11-heterosteroids

A.-L. Bottalla, M. Ibrahim-Ouali, M. Santelli, R. Furstoss, A. Archelas Advanced Synthesis§Catalysis 2007, 349(7), 1102-1110

Pages

Chapitres d'ouvrages (1)
RéférenceRésumé graphique
Alain Archelas, Gilles Iacazio, Michael Kotik. Epoxide hydrolase and its application in organic synthesis. Green Biocatalysis, 2016, 978-1-118-82229-6. 〈hal-01477037〉
Brevets (1)
RéférenceRésumé graphique
Véronique Alphand, Alain Archelas, Eva Boukhris-Uzan, Elise Courvoisier-Dezord, Lavoine-Hanneguelle Sophie. Method for Producing Lactones from a Strain of Aureobasidium Pullulans. France, Patent n° : PCT/FR2015/000042. 2015. 〈hal-01500973〉